A Seroepidemiologic Study of Reston Ebolavirus in Swine in the Philippines

Overview

Journal BMC Vet Res

Publisher Biomed Central

Specialty Veterinary Medicine

Date 2012 Jun 20

PMID 22709971

Citations 12

Authors

Yusuke Sayama

Catalino Demetria

Mariko Saito

Rachel R Azul

Satoshi Taniguchi

Shuetsu Fukushi

Tomoki Yoshikawa

Itoe Iizuka

Tetsuya Mizutani

Ichiro Kurane

Fidelino F Malbas Jr

Socorro Lupisan

Davinio P Catbagan

Samuel B Animas

Rieldrin G Morales

Emelinda L Lopez

Karen Rose C Dazo

Magdalena S Cruz

Remigio Olveda

Masayuki Saijo

Hitoshi Oshitani

Shigeru Morikawa

Affiliations

Soon will be listed here.

Abstract

Background: Ebola viruses cause viral hemorrhagic fever in humans and non-human primates and are endemic in Africa. Reston ebolavirus (REBOV) has caused several epizootics in cynomolgus monkeys (Macaca fascicularis) but is not associated with any human disease. In late 2008, REBOV infections were identified in swine for the first time in the Philippines.

Methods: A total of 215 swine sera collected at two REBOV-affected farms in 2008, in Pangasinan and Bulacan, were tested for the presence of REBOV-specific antibodies using multiple serodiagnosis systems. A total of 98 swine sera collected in a non-epizootic region, Tarlac, were also tested to clarify the prevalence of REBOV infection in the general swine population in the Philippines.

Results: Some 70 % of swine sera at the affected farms were positive for REBOV antibodies in the multiple serodiagnosis systems. On the other hand, none of the swine sera collected in Tarlac showed positive reactions in any of the diagnosis systems.

Conclusions: The high prevalence of REBOV infection in swine in the affected farms in 2008 suggests that swine is susceptible for REBOV infection. The multiple serological assays used in the study are thought to be useful for future surveillance of REOBV infection in swine in the Philippines.

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