» Articles » PMID: 22701893

Sorcin, a Potential Therapeutic Target for Reversing Multidrug Resistance in Cancer

Overview
Specialties Biochemistry
Physiology
Date 2012 Jun 16
PMID 22701893
Citations 5
Authors
Affiliations
Soon will be listed here.
Citing Articles

Clinical Significance and Prognostic Value of Human Soluble Resistance-Related Calcium-Binding Protein: A Pan-Cancer Analysis.

Zhang J, Chen J, Shan B, Lin L, Dong J, Sun Q Front Med (Lausanne). 2021; 8:752619.

PMID: 34869449 PMC: 8635117. DOI: 10.3389/fmed.2021.752619.


Broad regulation of gene isoform expression by Wnt signaling in cancer.

Idris M, Harmston N, Petretto E, Madan B, Virshup D RNA. 2019; 25(12):1696-1713.

PMID: 31506381 PMC: 6859862. DOI: 10.1261/rna.071506.119.


Binding of doxorubicin to Sorcin impairs cell death and increases drug resistance in cancer cells.

Genovese I, Fiorillo A, Ilari A, Masciarelli S, Fazi F, Colotti G Cell Death Dis. 2017; 8(7):e2950.

PMID: 28726784 PMC: 5550883. DOI: 10.1038/cddis.2017.342.


shRNA-mediated silencing of sorcin increases drug chemosensitivity in myeloma KM3/DDP and U266/ADM cell lines.

Xu P, Jiang Y, Wang J Int J Clin Exp Pathol. 2015; 8(3):2300-10.

PMID: 26045737 PMC: 4440046.


Resistance to paclitxel in breast carcinoma cells requires a quality control of mitochondrial antiapoptotic proteins by TRAP1.

Maddalena F, Sisinni L, Lettini G, Condelli V, Matassa D, Piscazzi A Mol Oncol. 2013; 7(5):895-906.

PMID: 23735188 PMC: 5528458. DOI: 10.1016/j.molonc.2013.04.009.

References
1.
Chuthapisith S, Bean B, Cowley G, Eremin J, Samphao S, Layfield R . Annexins in human breast cancer: Possible predictors of pathological response to neoadjuvant chemotherapy. Eur J Cancer. 2009; 45(7):1274-1281. DOI: 10.1016/j.ejca.2008.12.026. View

2.
Zamparelli C, Ilari A, Verzili D, VECCHINI P, CHIANCONE E . Calcium- and pH-linked oligomerization of sorcin causing translocation from cytosol to membranes. FEBS Lett. 1997; 409(1):1-6. DOI: 10.1016/s0014-5793(97)00464-x. View

3.
Fowler M, Colotti G, Chiancone E, Smith G, Fearon I . Sorcin modulates cardiac L-type Ca2+ current by functional interaction with the alpha1C subunit in rabbits. Exp Physiol. 2008; 93(12):1233-8. DOI: 10.1113/expphysiol.2008.043497. View

4.
Xie X, Dwyer M, Swenson L, Parker M, Botfield M . Crystal structure of calcium-free human sorcin: a member of the penta-EF-hand protein family. Protein Sci. 2001; 10(12):2419-25. PMC: 2374028. DOI: 10.1110/ps.36701. View

5.
Brownawell A, Creutz C . Calcium-dependent binding of sorcin to the N-terminal domain of synexin (annexin VII). J Biol Chem. 1997; 272(35):22182-90. DOI: 10.1074/jbc.272.35.22182. View