Herpes Simplex Virus and Varicella Zoster Virus, the House Guests Who Never Leave

Overview

Journal Herpesviridae

Publisher Biomed Central

Date 2012 Jun 14

PMID 22691604

Citations 45

Authors

Paul R Kinchington

Anthony J St Leger

Jean-Marc G Guedon

Robert L Hendricks

Affiliations

Soon will be listed here.

Abstract

Human alphaherpesviruses including herpes simplex viruses (HSV-1, HSV-2) and varicella zoster virus (VZV) establish persistent latent infection in sensory neurons for the life of the host. All three viruses have the potential to reactivate causing recurrent disease. Regardless of the homology between the different virus strains, the three viruses are characterized by varying pathologies. This review will highlight the differences in infection pattern, immune response, and pathogenesis associated with HSV-1 and VZV.

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