» Articles » PMID: 22676939

Phosphodiesterase-4 Activity: a Critical Modulator of Atrial Contractility and Arrhythmogenesis

Overview
Date 2012 Jun 9
PMID 22676939
Citations 5
Authors
Affiliations
Soon will be listed here.
Citing Articles

The Dysfunction of Ca Channels in Hereditary and Chronic Human Heart Diseases and Experimental Animal Models.

Shemarova I Int J Mol Sci. 2023; 24(21).

PMID: 37958665 PMC: 10650855. DOI: 10.3390/ijms242115682.


Various subtypes of phosphodiesterase inhibitors differentially regulate pulmonary vein and sinoatrial node electrical activities.

Lin Y, Cheng C, Huang J, Chen Y, Lu Y, Chen Y Exp Ther Med. 2020; 19(4):2773-2782.

PMID: 32256760 PMC: 7086206. DOI: 10.3892/etm.2020.8495.


A dominant variant in the PDE1C gene is associated with nonsyndromic hearing loss.

Wang L, Feng Y, Yan D, Qin L, Grati M, Mittal R Hum Genet. 2018; 137(6-7):437-446.

PMID: 29860631 PMC: 6560636. DOI: 10.1007/s00439-018-1895-y.


Suppression of spontaneous ca elevations prevents atrial fibrillation in calsequestrin 2-null hearts.

Faggioni M, Savio-Galimberti E, Venkataraman R, Hwang H, Kannankeril P, Darbar D Circ Arrhythm Electrophysiol. 2014; 7(2):313-20.

PMID: 24493699 PMC: 3989424. DOI: 10.1161/CIRCEP.113.000994.


Highlights of the year in JACC 2012.

DeMaria A, Bax J, Feld G, Greenberg B, Hall J, Hlatky M J Am Coll Cardiol. 2013; 61(3):357-85.

PMID: 23328613 PMC: 3760511. DOI: 10.1016/j.jacc.2012.12.002.

References
1.
Pfeufer A, van Noord C, Marciante K, Arking D, Larson M, Smith A . Genome-wide association study of PR interval. Nat Genet. 2010; 42(2):153-9. PMC: 2850197. DOI: 10.1038/ng.517. View

2.
Li Q, Himmel H, Ravens U . Effects of the new phosphodiesterase-III inhibitor R80122 on contractility and calcium current in human cardiac tissue. J Cardiovasc Pharmacol. 1994; 24(1):133-43. DOI: 10.1097/00005344-199407000-00021. View

3.
Christ T, Engel A, Ravens U, Kaumann A . Cilostamide potentiates more the positive inotropic effects of (-)-adrenaline through beta(2)-adrenoceptors than the effects of (-)-noradrenaline through beta (1)-adrenoceptors in human atrial myocardium. Naunyn Schmiedebergs Arch Pharmacol. 2006; 374(3):249-53. DOI: 10.1007/s00210-006-0119-5. View

4.
Christ T, Galindo-Tovar A, Thoms M, Ravens U, Kaumann A . Inotropy and L-type Ca2+ current, activated by beta1- and beta2-adrenoceptors, are differently controlled by phosphodiesterases 3 and 4 in rat heart. Br J Pharmacol. 2009; 156(1):62-83. PMC: 2697770. DOI: 10.1111/j.1476-5381.2008.00015.x. View

5.
Van Wagoner D, Pond A, Lamorgese M, Rossie S, McCarthy P, Nerbonne J . Atrial L-type Ca2+ currents and human atrial fibrillation. Circ Res. 1999; 85(5):428-36. DOI: 10.1161/01.res.85.5.428. View