Frailty and Its Impact on Health-related Quality of Life: a Cross-sectional Study on Elder Community-dwelling Preventive Health Service Users

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2012 Jun 5

PMID 22662268

Citations 48

Authors

Yaw-Wen Chang

Wei-Liang Chen

Fu-Gong Lin

Wen-Hui Fang

Ming-Yung Yen

Chia-Chuan Hsieh

Tung-Wei Kao

Affiliations

Soon will be listed here.

Abstract

Background: The purpose of this study was to identify the incidence of frailty and to investigate the relationship between frailty status and health-related quality of life (HRQoL) in the community-dwelling elderly population who utilize preventive health services.

Methods: People aged 65 years and older who visited a medical center in Taipei City from March to August in 2011 for an annual routine check-up provided by the National Health Insurance were eligible. A total of 374 eligible elderly adults without cognitive impairment had a mean age of 74.6±6.3 years. Frailty status was determined according to the Fried frailty criteria. HRQoL was measured with Short Form-36 (SF-36). Multiple regression analyses examined the relationship between frailty status and the two summary scales of SF-36. Models were adjusted for the participants' sociodemographic and health status.

Results: After adjusting for sociodemographic and health-related covariables, frailty was found to be more significantly associated (p<0.001) with lower scores on both physical and mental health-related quality of life summary scales compared with robustness. For the frailty phenotypes, slowness represented the major contributing factor in the physical component scale of SF-36, and exhaustion was the primary contributing factor in the mental component scale.

Conclusion: The status of frailty is closely associated with HRQoL in elderly Taiwanese preventive health service users. The impacts of frailty phenotypes on physical and mental aspects of HRQoL differ.

Citing Articles

Bidirectional association between frailty and quality of life within English longitudinal study of aging.

Alattas A, Shuweihdi F, Best K, Nikolova S, West R Qual Life Res. 2024; 34(1):261-271.

PMID: 39400690 PMC: 11802669. DOI: 10.1007/s11136-024-03809-7.

Physical Health-Related Quality of Life and Postsurgical Outcomes in Brain Tumor Resection Patients.

Chintapalli R Asian J Neurosurg. 2024; 19(3):412-418.

PMID: 39205899 PMC: 11349402. DOI: 10.1055/s-0044-1787674.

Influence of frailty status on the health-related quality of life in older patients with chronic low back pain: a retrospective observational study.

Kim H, Jun B, Lee H, Kim S Qual Life Res. 2024; 33(7):1905-1913.

PMID: 38642220 DOI: 10.1007/s11136-024-03658-4.

Characteristics associated with poor atrial fibrillation-related quality of life in adults with atrial fibrillation.

Pierre-Louis I, Saczynski J, Lopez-Pintado S, Waring M, Abu H, Goldberg R J Cardiovasc Med (Hagerstown). 2023; 24(7):422-429.

PMID: 37129916 PMC: 10699883. DOI: 10.2459/JCM.0000000000001479.

COVID-19 in Elderly Patients Receiving Haemodialysis: A Current Review.

McDonnell T, Wu H, Kalra P, Chinnadurai R Biomedicines. 2023; 11(3).

PMID: 36979905 PMC: 10046485. DOI: 10.3390/biomedicines11030926.

References

Pfeiffer E . A short portable mental status questionnaire for the assessment of organic brain deficit in elderly patients. J Am Geriatr Soc. 1975; 23(10):433-41. DOI: 10.1111/j.1532-5415.1975.tb00927.x. View

Syddall H, Roberts H, Evandrou M, Cooper C, Bergman H, Sayer A . Prevalence and correlates of frailty among community-dwelling older men and women: findings from the Hertfordshire Cohort Study. Age Ageing. 2009; 39(2):197-203. PMC: 3546311. DOI: 10.1093/ageing/afp204. View

Masel M, Graham J, Reistetter T, Markides K, Ottenbacher K . Frailty and health related quality of life in older Mexican Americans. Health Qual Life Outcomes. 2009; 7:70. PMC: 2724500. DOI: 10.1186/1477-7525-7-70. View

Podsiadlo D, Richardson S . The timed "Up & Go": a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. 1991; 39(2):142-8. DOI: 10.1111/j.1532-5415.1991.tb01616.x. View

Chen H, Wu C, Lee Y, Liao S, Lee M . Validity of the five-item Brief Symptom Rating Scale among subjects admitted for general health screening. J Formos Med Assoc. 2006; 104(11):824-9. View

Boey K . Cross-validation of a short form of the CES-D in Chinese elderly. Int J Geriatr Psychiatry. 1999; 14(8):608-17. DOI: 10.1002/(sici)1099-1166(199908)14:8<608::aid-gps991>3.0.co;2-z. View

Liou Y, Jwo C, Grace Yao K, Chiang L, Huang L . Selection of appropriate Chinese terms to represent intensity and types of physical activity terms for use in the Taiwan version of IPAQ. J Nurs Res. 2008; 16(4):252-63. DOI: 10.1097/01.jnr.0000387313.20386.0a. View

Cesari M, Kritchevsky S, Newman A, Simonsick E, Harris T, Penninx B . Added value of physical performance measures in predicting adverse health-related events: results from the Health, Aging And Body Composition Study. J Am Geriatr Soc. 2009; 57(2):251-9. PMC: 2695653. DOI: 10.1111/j.1532-5415.2008.02126.x. View

Lee M, Liao S, Lee Y, Wu C, Tseng M, Gau S . Development and verification of validity and reliability of a short screening instrument to identify psychiatric morbidity. J Formos Med Assoc. 2003; 102(10):687-94. View

10.

Ware J, Kosinski M . Interpreting SF-36 summary health measures: a response. Qual Life Res. 2002; 10(5):405-13; discussion 415-20. DOI: 10.1023/a:1012588218728. View

11.

Bandeen-Roche K, Xue Q, Ferrucci L, Walston J, Guralnik J, Chaves P . Phenotype of frailty: characterization in the women's health and aging studies. J Gerontol A Biol Sci Med Sci. 2006; 61(3):262-6. DOI: 10.1093/gerona/61.3.262. View

12.

Studenski S, Perera S, Patel K, Rosano C, Faulkner K, Inzitari M . Gait speed and survival in older adults. JAMA. 2011; 305(1):50-8. PMC: 3080184. DOI: 10.1001/jama.2010.1923. View

13.

Avila-Funes J, Helmer C, Amieva H, Barberger-Gateau P, Le Goff M, Ritchie K . Frailty among community-dwelling elderly people in France: the three-city study. J Gerontol A Biol Sci Med Sci. 2008; 63(10):1089-96. PMC: 4749670. DOI: 10.1093/gerona/63.10.1089. View

14.

Fillit H, Butler R . The frailty identity crisis. J Am Geriatr Soc. 2009; 57(2):348-52. DOI: 10.1111/j.1532-5415.2008.02104.x. View

15.

Wong C, Weiss D, Sourial N, Karunananthan S, Quail J, Wolfson C . Frailty and its association with disability and comorbidity in a community-dwelling sample of seniors in Montreal: a cross-sectional study. Aging Clin Exp Res. 2009; 22(1):54-62. DOI: 10.1007/BF03324816. View

16.

Frisoli Jr A, Chaves P, Ingham S, Fried L . Severe osteopenia and osteoporosis, sarcopenia, and frailty status in community-dwelling older women: results from the Women's Health and Aging Study (WHAS) II. Bone. 2011; 48(4):952-7. DOI: 10.1016/j.bone.2010.12.025. View

17.

Fuh J, Wang S, Lu S, Juang K, Lee S . Psychometric evaluation of a Chinese (Taiwanese) version of the SF-36 health survey amongst middle-aged women from a rural community. Qual Life Res. 2001; 9(6):675-83. DOI: 10.1023/a:1008993821633. View

18.

Ware Jr J, Sherbourne C . The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992; 30(6):473-83. View

19.

Lin C, Li C, Chang C, Liu C, Lin C, Meng N . Reduced health-related quality of life in elders with frailty: a cross-sectional study of community-dwelling elders in Taiwan. PLoS One. 2011; 6(7):e21841. PMC: 3128625. DOI: 10.1371/journal.pone.0021841. View

20.

Ferrucci L, Guralnik J, Studenski S, Fried L, Cutler Jr G, Walston J . Designing randomized, controlled trials aimed at preventing or delaying functional decline and disability in frail, older persons: a consensus report. J Am Geriatr Soc. 2004; 52(4):625-34. DOI: 10.1111/j.1532-5415.2004.52174.x. View