Migraine and Cardiovascular Diseases
Overview
Affiliations
Migraine has complex relationships with cerebrovascular and cardiovascular disorders but also with cardiac anomalies. Patients affected by migraine with aura have an increased prevalence of right-to-left shunt due to patent foramen ovale or pulmonary arteriovenous malformations. The association between ischemic heart disease, cardiovascular mortality and migraine remains unsettled. The debate focuses on a physiopathological link between migraine and cardiovascular diseases or a higher prevalence of risk factors in migraineurs.
Genetic and biochemical changes of the serotonergic system in migraine pathobiology.
Gasparini C, Smith R, Griffiths L J Headache Pain. 2017; 18(1):20.
PMID: 28194570 PMC: 5307402. DOI: 10.1186/s10194-016-0711-0.
Kalaycioglu E, Gokdeniz T, Aykan A, Gursoy M, Gul I, Ayhan N Int J Cardiovasc Imaging. 2014; 30(7):1255-63.
PMID: 24859191 DOI: 10.1007/s10554-014-0456-2.
Studies on the pathophysiology and genetic basis of migraine.
Gasparini C, Sutherland H, Griffiths L Curr Genomics. 2014; 14(5):300-15.
PMID: 24403849 PMC: 3763681. DOI: 10.2174/13892029113149990007.