Thymic Neoplasms: a Clinical Update

Overview

Journal Curr Oncol Rep

Publisher Current Science

Specialty Oncology

Date 2012 May 29

PMID 22639107

Citations 8

Authors

Mark Mikhail

Yasmin Mekhail

Tarek Mekhail

Affiliations

Soon will be listed here.

Abstract

Thymoma is a unique neoplasm of the anterior mediastinum that is frequently associated with indolent growth and a variety of paraneoplastic syndromes. One third of cases are detected during the evaluation of myasthenia gravis. Classification systems of thymoma have limited ability in accurately predicting prognosis and course of disease. Thus, staging is the only way to predict clinical behavior. Encapsulated tumors that are surgically resected carry the best prognosis. Adjuvant radiotherapy is recommended for incompletely excised and most invasive thymomas. Chemotherapy in anthracycline-based chemotherapy remains the most effective chemotherapy for neoadjuvant, adjuvant or palliative treatment.

Citing Articles

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Tc MIBI THYMIC SCINTIGRAPHY IN DIAGNOSIS AND THERAPEUTIC DECISION MAKING: WHAT IS BEHIND THE IMAGE?.

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Malignant thymoma with metastasis associated with paraneoplastic myasthenia gravis.

Jazi H, Harmon D, Tran T, Denham C Proc (Bayl Univ Med Cent). 2017; 30(3):330-332.

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Development of combined thymic carcinoma and thymoma in an extrathymic lesion during long follow-up for recurrent thymoma.

Ohue Y, Matsuoka S, Kumeda H, Agatsuma H, Hyougotani A, Toishi M Mol Clin Oncol. 2016; 4(2):139-142.

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