Parvovirus B19 Infection and Severe Anemia in Renal Transplant Recipients

Overview

Journal ScientificWorldJournal

Publisher Wiley

Specialty Biology

Date 2012 May 24

PMID 22619569

Citations 4

Authors

Antonio Carraturo

Valentina Catalani

Donatella Ottaviani

Patrizia Menichelli

Maurizio Rossini

Delia Terella

Brunello Biondi

Affiliations

Soon will be listed here.

Abstract

Kidney transplant (KT) recipients can develop symptomatic Parvovirus (PV) B19 infections, frequently associated with persistent anemia. The aim of this study was to evaluate the prevalence and clinical significance of PV B19 infection in anemic and non-anemic KT patients. Overall, out of 64 patients monitored for the presence of PV B19 by real-time PCR, 2 (3.12%) had an active PV B19 infection, in absence of other viral coinfections. The 2 cases occurred in nonanemic kidney transplant patients group (2/50, 4%), while none of the anemic transplant patients (0/14) was found to suffer from this infection. Moreover, patients affected by active PV B19 infection showed viral loads not exceeding 1 × 10(5) genome copies/reaction. In conclusion, in this study, PV B19 infection was not common in renal transplant population and wasn't associated with severe anemia.

Citing Articles

Parvovirus B19 status in liver, kidney and pancreas transplant candidates: A single center experience.

Simunov B, Mrzljak A, Jurekovic Z, Zidovec Lepej S, Bainrauch A, Pavicic Saric J World J Transplant. 2022; 12(11):378-387.

PMID: 36437842 PMC: 9693899. DOI: 10.5500/wjt.v12.i11.378.

Epidemiology of parvovirus B19 and anemia among kidney transplant recipients: A meta-analysis.

Thongprayoon C, Khoury N, Bathini T, Aeddula N, Boonpheng B, Lertjitbanjong P Urol Ann. 2020; 12(3):241-247.

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Human Parvovirus B19 and blood product safety: a tale of twenty years of improvements.

Marano G, Vaglio S, Pupella S, Facco G, Calizzani G, Candura F Blood Transfus. 2015; 13(2):184-96.

PMID: 25849894 PMC: 4385066. DOI: 10.2450/2014.0174.14.

The effects of co-infection with human parvovirus B19 and Plasmodium falciparum on type and degree of anaemia in Ghanaian children.

Duedu K, Sagoe K, Ayeh-Kumi P, Affrim R, Adiku T Asian Pac J Trop Biomed. 2013; 3(2):129-39.

PMID: 23593592 PMC: 3627173. DOI: 10.1016/S2221-1691(13)60037-4.

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