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Intrauterine Extremity Gangrene and Cerebral Infarction at Term: a Case Report

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Publisher Wiley
Specialty Pediatrics
Date 2012 May 19
PMID 22606511
Citations 5
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Abstract

Intrauterine extremity gangrene in combination with cerebral infarction is a serious and rare event. We present a case with a healthy mother who gave birth to a child with this condition. At term, the mother presented at the antenatal clinic with decreased fetal movements. Cardiotocography (CTG) showed signs of fetal distress and a caesarean section was performed. The left arm of the newborn was found gangrenous. Amputation of the arm was necessary and the child was subsequently treated with anticoagulant therapy due to thrombosis and cerebral infarction in the left hemisphere found by magnetic resonance imaging (MRI). At one year of age the boy was doing well and had prosthesis as a left arm. He had no signs of further complications. Despite thorough examination of the parents and the child, the reason for the thrombosis is still unknown.

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References
1.
Turnpenny P, Stahl S, Bowers D, Bingham P . Peripheral ischaemia and gangrene presenting at birth. Eur J Pediatr. 1992; 151(8):550-4. DOI: 10.1007/BF01957717. View

2.
Smorgick N, Herman A, Wiener Y, Halperin R, Sherman D . Prenatal thrombosis of the inferior vena cava and the renal veins. Prenat Diagn. 2007; 27(7):603-7. DOI: 10.1002/pd.1739. View

3.
Guajardo L, Strauss A, Amster J . Idiopathic cerebral infarction and upper limb ischemia in neonates. Am J Perinatol. 1994; 11(2):119-22. DOI: 10.1055/s-2007-994570. View

4.
Carr M, Al-Qattan M, Clarke H . Extremity gangrene in utero. J Hand Surg Br. 1996; 21(5):652-5. DOI: 10.1016/s0266-7681(96)80152-5. View

5.
Asindi A, Stephenson J, Young D . Spastic hemiparesis and presumed prenatal embolisation. Arch Dis Child. 1988; 63(1):68-9. PMC: 1779330. DOI: 10.1136/adc.63.1.68. View