Predictors of Effects of Lifestyle Intervention on Diabetes Mellitus Type 2 Patients

Overview

Journal ScientificWorldJournal

Publisher Wiley

Specialty Biology

Date 2012 May 18

PMID 22593714

Authors

Ramune Jacobsen

Eva Vadstrup

Michael Roder

Anne Frolich

Affiliations

Soon will be listed here.

Abstract

The main aim of the study was to identify predictors of the effects of lifestyle intervention on diabetes mellitus type 2 patients by means of multivariate analysis. Data from a previously published randomised clinical trial, which compared the effects of a rehabilitation programme including standardised education and physical training sessions in the municipality's health care centre with the same duration of individual counseling in the diabetes outpatient clinic, were used. Data from 143 diabetes patients were analysed. The merged lifestyle intervention resulted in statistically significant improvements in patients' systolic blood pressure, waist circumference, exercise capacity, glycaemic control, and some aspects of general health-related quality of life. The linear multivariate regression models explained 45% to 80% of the variance in these improvements. The baseline outcomes in accordance to the logic of the regression to the mean phenomenon were the only statistically significant and robust predictors in all regression models. These results are important from a clinical point of view as they highlight the more urgent need for and better outcomes following lifestyle intervention for those patients who have worse general and disease-specific health.

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