Production of Plasminogen Activator by Human and Hamster Cells Infected with Human Cytomegalovirus

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 1979 Aug 1

PMID 225562

Citations 6

Authors

K Yamanishi

F Rapp

Affiliations

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Abstract

Plasminogen activator was produced by both human embryo fibroblasts (a permissive system) and hamster embryo fibroblasts (a nonpermissive system) after exposure to human cytomegalovirus. The level of this activator was measured by using plates coated with [125I]fibrin. The production of plasminogen activator was enhanced when the human cells were exposed to human cytomegalovirus previously irradiated with UV light (5,520 to 55,200 ergs/mm2).

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References

Hirai K, Maeda F, Watanabe Y . Expression of early virus functions in human cytomegalovirus infected HEL cells: effect of ultraviolet light-irradiation of the virus. J Gen Virol. 1978; 38(1):121-33. DOI: 10.1099/0022-1317-38-1-121. View

Hirai K, Watanabe Y . Induction of alpha type DNA polymerases in human cytomegalovirus-infected WI-38 cells. Biochim Biophys Acta. 1976; 447(3):328-39. DOI: 10.1016/0005-2787(76)90056-3. View

ESTES J, Huang E . Stimulation of cellular thymidine kinases by human cytomegalovirus. J Virol. 1977; 24(1):13-21. PMC: 515905. DOI: 10.1128/JVI.24.1.13-21.1977. View

Zavada V, Erban V, Rezacova D, Vonka V . Thymidine-kinase in cytomegalovirus infected cells. Arch Virol. 1976; 52(4):333-9. DOI: 10.1007/BF01315622. View

Yamanishi K, Fogel M, Rapp F . Effect of caffeine on the replication of nonirradiated and ultraviolet-irradiated cytomegalovirus. Intervirology. 1978; 10(4):241-53. DOI: 10.1159/000148987. View

Isom H . Stimulation of ornithine decarboxylase by human cytomegalovirus. J Gen Virol. 1979; 42(2):265-78. DOI: 10.1099/0022-1317-42-2-265. View

Howett M, High C, Rapp F . Production of plasminogen activator by cells transformed by herpesviruses. Cancer Res. 1978; 38(4):1075-8. View

Stinski M . Synthesis of proteins and glycoproteins in cells infected with human cytomegalovirus. J Virol. 1977; 23(3):751-67. PMC: 515887. DOI: 10.1128/JVI.23.3.751-767.1977. View

Christman J, Acs G . Purification and characterization of a cellular fibrinolytic factor associated with oncogenic transformation: the plasminogen activator from SV-40-transformed hamster cells. Biochim Biophys Acta. 1974; 340(3):339-47. DOI: 10.1016/0005-2787(74)90279-2. View

10.

Unkeless J, Dano K, KELLERMAN G, Reich E . Fibrinolysis associated with oncogenic transformation. Partial purification and characterization of the cell factor, a plasminogen activator. J Biol Chem. 1974; 249(13):4295-305. View

11.

OSSOWSKI L, Quigley J, Reich E . Fibrinolysis associated with oncogenic transformation. Morphological correlates. J Biol Chem. 1974; 249(13):4312-20. View

12.

Lang D, Montagnier L, LATARJET R . Growth in agarose of human cells infected with cytomegalovirus. J Virol. 1974; 14(2):327-32. PMC: 355518. DOI: 10.1128/JVI.14.2.327-332.1974. View

13.

Seemayer N, Defendi V . Analysis of minimal functions of simian virus 40. 3. Evidence for "host cell repair" of oncogenicity and infectivity of UV-irradiated simian virus 40. J Virol. 1974; 13(1):36-41. PMC: 355255. DOI: 10.1128/JVI.13.1.36-41.1974. View

14.

Unkeless J, Tobia A, OSSOWSKI L, Quigley J, Rifkin D, Reich E . An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. I. Chick embryo fibroblast cultures transformed by avian RNA tumor viruses. J Exp Med. 1973; 137(1):85-111. PMC: 2139356. DOI: 10.1084/jem.137.1.85. View

15.

Albrecht T, Rapp F . Malignant transformation of hamster embryo fibroblasts following exposure to ultraviolet-irradiated human cytomegalovirus. Virology. 1973; 55(1):53-61. DOI: 10.1016/s0042-6822(73)81007-4. View

16.

Furukawa T, Fioretti A, Plotkin S . Growth characteristics of cytomegalovirus in human fibroblasts with demonstration of protein synthesis early in viral replication. J Virol. 1973; 11(6):991-7. PMC: 355208. DOI: 10.1128/JVI.11.6.991-997.1973. View

17.

Duff R, Rapp F . Quantitative characteristics of the transformation of hamster cells by PARA (defective simian virus 40)-adenovirus 7. J Virol. 1970; 5(5):568-77. PMC: 376042. DOI: 10.1128/JVI.5.5.568-577.1970. View

18.

WENTWORTH B, French L . Plaque assay of cytomegalovirus strains of human origin. Proc Soc Exp Biol Med. 1970; 135(2):253-8. DOI: 10.3181/00379727-135-35031. View

19.

Furukawa T, Sakuma S, Plotkin S . Human cytomegalovirus infection of WI-38 cells stimulates mitochondrial DNA synthesis. Nature. 1976; 262(5567):414-6. DOI: 10.1038/262414a0. View

20.

Albrecht T, Nachtigal M, St Jeor S, Rapp F . Induction of cellular DNA synthesis and increased mitotic activity in syrian hamster embryo cells abortively infected with human cytomegalovirus. J Gen Virol. 1976; 30(2):167-77. DOI: 10.1099/0022-1317-30-2-167. View