High C + G Content in Parapoxvirus DNA

Overview

Journal J Gen Virol

Specialty Microbiology

Date 1979 Apr 1

PMID 225418

Citations 21

Authors

R Wittek

C C KUENZLE

R Wyler

Affiliations

Soon will be listed here.

Abstract

The DNAs of eight parapoxviruses (four stomatitis papulosa viruses isolated from infected calves, a pseudocowpox virus isolated from a teat lesion of an infected cow and three orf viruses, one isolated from an infected sheep and two isolated from human infections) were analysed in CsCl gradients. The mole % of G+C was calculated from the buoyant density and found to be approx. 63% for all virus isolates examined. Parapoxvirus DNA thus has by far the highest G+C content of all poxvirus DNAs so far examined.

Citing Articles

Expression of F1L, a vaccinia virus H3L transmembrane protein analogue of orf virus, and its successful purification as a diagnostic antigen.

Golmei P, Venkatesan G, Kushwaha A, Kumar A, Mondal B Virus Genes. 2024; 60(6):642-651.

PMID: 39136814 DOI: 10.1007/s11262-024-02097-0.

Molecular characterization and phylogenetic analysis of orf virus isolated from goats in Sokoto metropolis, Nigeria.

Lawal N, Ibrahim M, Onawala D, Bello M, Aliyu R, Baraya Y Future Sci OA. 2021; 7(6):FSO700.

PMID: 34046202 PMC: 8147748. DOI: 10.2144/fsoa-2020-0162.

Genomic Features and Evolution of the Parapoxvirus during the Past Two Decades.

Yao X, Pang M, Wang T, Chen X, Tang X, Chang J Pathogens. 2020; 9(11).

PMID: 33120928 PMC: 7694016. DOI: 10.3390/pathogens9110888.

Orf Virus Encoded Protein ORFV119 Induces Cell Apoptosis Through the Extrinsic and Intrinsic Pathways.

Li W, Chen H, Deng H, Kuang Z, Long M, Chen D Front Microbiol. 2018; 9:1056.

PMID: 29896166 PMC: 5986898. DOI: 10.3389/fmicb.2018.01056.

Molecular genetic analysis of orf virus: a poxvirus that has adapted to skin.

Fleming S, Wise L, Mercer A Viruses. 2015; 7(3):1505-39.

PMID: 25807056 PMC: 4379583. DOI: 10.3390/v7031505.