Self-reported Versus 'true' Adherence in Heart Failure Patients: a Study Using the Medication Event Monitoring System

Overview

Journal Neth Heart J

Specialty Cardiology & Vascular Diseases

Date 2012 Apr 25

PMID 22527915

Citations 29

Authors

M M W Nieuwenhuis

T Jaarsma

D J van Veldhuisen

M H L van der Wal

Affiliations

Soon will be listed here.

Abstract

Background: Adherence to (non)pharmacological treatment is important in heart failure (HF) patients, since it leads to better clinical outcome. Although self-reported and objectively measured medication adherence in HF patients have been compared in previous studies, none of these studies have used an evidence-based cutpoint to differentiate between adherence and non-adherence.

Methods: In 37 HF patients (mean age 68 ± 10 years, 27 % female, 40 % NYHA functional class III-IV), medication (ACEi/ARB) adherence was objectively measured using the Medication Event Monitoring System (MEMS). Adherence to and importance of taking medication was also assessed by self-report using the Revised HF Compliance Questionnaire.

Results: All patients reported that adherence was (highly) important to them and that they 'always' took their medication as prescribed (i.e. 100 % adherence). However, when measured by the MEMS, only 76 % of all patients were adherent. Non-adherent patients more often had a complex medication regimen (78 % vs. 21 %, P < .01), more often depressive symptoms (75 % vs. 29 %, P = .04) and a shorter history of HF (8 vs. 41 months, P = .04), compared with adherent patients.

Conclusions: Medication adherence measured by the MEMS was remarkably lower than self-reported adherence. Given the evidence of its importance, further efforts are needed to improve adherence to the pharmacological regimen in HF patients.

Citing Articles

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Medication Adherence and Its Associated Factors Among Outpatients with Heart Failure.

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The Role of Depression on Treatment Adherence in Patients with Heart Failure-a Systematic Review of the Literature.

Poletti V, Pagnini F, Banfi P, Volpato E Curr Cardiol Rep. 2022; 24(12):1995-2008.

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