Pancreatic Perfusion CT in Early Stage of Severe Acute Pancreatitis

Overview

Journal Int J Inflam

Publisher Wiley

Date 2012 Apr 21

PMID 22518337

Citations 9

Authors

Yoshihisa Tsuji

Naoki Takahashi

Chiba Tsutomu

Affiliations

Soon will be listed here.

Abstract

Early intensive care for severe acute pancreatitis is essential for improving SAP mortality rates. However, intensive therapies for SAP are often delayed because there is no ideal way to accurately evaluate severity in the early stages. Currently, perfusion CT has been shown useful to predict prognosis of SAP in the early stage. In this presented paper, we would like to review the clinical usefulness and limitations of perfusion CT for evaluation of local and systemic complications in early stage of SAP.

Citing Articles

A Case Report of Acute Necrotizing Pancreatitis after COVID-19 Infection.

Salehi A, Salehi H, Hasanzarrini M, Jenabi E, Alizamir A Case Rep Med. 2022; 2022:3258677.

PMID: 35935668 PMC: 9355785. DOI: 10.1155/2022/3258677.

Neutrophil Gelatinase-Associated Lipocalin Protects Acinar Cells From Cerulein-Induced Damage During Acute Pancreatitis.

Bhatia R, Muniyan S, Thompson C, Kaur S, Jain M, Singh R Pancreas. 2020; 49(10):1297-1306.

PMID: 33122517 PMC: 8056863. DOI: 10.1097/MPA.0000000000001690.

Can Disturbed Liver Perfusion Revealed in p-CT on the First Day of Acute Pancreatitis Provide Information about the Expected Severity of the Disease?.

Pienkowska J, Gwozdziewicz K, Skrobisz K, Czarnowska-Cubala M, Kozak O, Hac S Gastroenterol Res Pract. 2019; 2019:6590729.

PMID: 31485219 PMC: 6710743. DOI: 10.1155/2019/6590729.

Predicative values of C-reactive protein for the therapeutic effects of ulinastatin combined with somatostatin in severe acute pancreatitis and for the severity of gastrointestinal failure.

Wang Y, Li L Exp Ther Med. 2018; 16(4):3165-3171.

PMID: 30233671 PMC: 6143877. DOI: 10.3892/etm.2018.6577.

Early diagnosis of pancreatic necrosis based on perfusion CT to predict the severity of acute pancreatitis.

Tsuji Y, Takahashi N, Isoda H, Koizumi K, Koyasu S, Sekimoto M J Gastroenterol. 2017; 52(10):1130-1139.

PMID: 28374057 DOI: 10.1007/s00535-017-1330-5.

References

Goh V, Dattani M, Farwell J, Shekhdar J, Tam E, Patel S . Radiation dose from volumetric helical perfusion CT of the thorax, abdomen or pelvis. Eur Radiol. 2010; 21(5):974-81. DOI: 10.1007/s00330-010-1997-y. View

Sitek A, Sheiman R . Small-bowel perfusion measurement: feasibility with single-compartment kinetic model applied to dynamic contrast-enhanced CT. Radiology. 2005; 237(2):670-4. DOI: 10.1148/radiol.2372041403. View

Tsushima Y, Miyazaki M, Taketomi-Takahashi A, Endo K . Feasibility of measuring human pancreatic perfusion in vivo using imaging techniques. Pancreas. 2011; 40(5):747-52. DOI: 10.1097/MPA.0b013e318215ac22. View

Piascik M, Rydzewska G, Milewski J, Olszewski S, Furmanek M, Walecki J . The results of severe acute pancreatitis treatment with continuous regional arterial infusion of protease inhibitor and antibiotic: a randomized controlled study. Pancreas. 2010; 39(6):863-7. DOI: 10.1097/MPA.0b013e3181d37239. View

Chauhan S, Forsmark C . The difficulty in predicting outcome in acute pancreatitis. Am J Gastroenterol. 2010; 105(2):443-5. DOI: 10.1038/ajg.2009.623. View

Tsuji Y, Hamaguchi K, Watanabe Y, Okumura A, Isoda H, Yamamoto N . Perfusion CT is superior to angiography in predicting pancreatic necrosis in patients with severe acute pancreatitis. J Gastroenterol. 2010; 45(11):1155-62. DOI: 10.1007/s00535-010-0267-8. View

Petrov M, Shanbhag S, Chakraborty M, Phillips A, Windsor J . Organ failure and infection of pancreatic necrosis as determinants of mortality in patients with acute pancreatitis. Gastroenterology. 2010; 139(3):813-20. DOI: 10.1053/j.gastro.2010.06.010. View

Bize P, Platon A, Becker C, Poletti P . Perfusion measurement in acute pancreatitis using dynamic perfusion MDCT. AJR Am J Roentgenol. 2005; 186(1):114-8. DOI: 10.2214/AJR.04.1416. View

Takeda K, Mikami Y, Fukuyama S, Egawa S, Sunamura M, Ishibashi T . Pancreatic ischemia associated with vasospasm in the early phase of human acute necrotizing pancreatitis. Pancreas. 2005; 30(1):40-9. View

10.

Sheiman R, Sitek A . Feasibility of measurement of pancreatic perfusion parameters with single-compartment kinetic model applied to dynamic contrast-enhanced CT images. Radiology. 2008; 249(3):878-82. DOI: 10.1148/radiol.2492080026. View

11.

Miles K . Perfusion CT for the assessment of tumour vascularity: which protocol?. Br J Radiol. 2004; 76 Spec No 1:S36-42. DOI: 10.1259/bjr/18486642. View

12.

Yu L, Li H, Fletcher J, McCollough C . Automatic selection of tube potential for radiation dose reduction in CT: a general strategy. Med Phys. 2010; 37(1):234-43. DOI: 10.1118/1.3264614. View

13.

Tsuji Y, Koizumi K, Isoda H, Ueno K, Tada S, Chiba T . The radiological exposure of pancreatic perfusion computed tomography. Pancreas. 2010; 39(4):541. DOI: 10.1097/MPA.0b013e3181c16037. View

14.

Warndorf M, Kurtzman J, Bartel M, Cox M, MacKenzie T, Robinson S . Early fluid resuscitation reduces morbidity among patients with acute pancreatitis. Clin Gastroenterol Hepatol. 2011; 9(8):705-9. PMC: 3143229. DOI: 10.1016/j.cgh.2011.03.032. View

15.

Hackert T, Werner J, Uhl W, Gebhard M, Buchler M, Schmidt J . Reduction of ischemia/reperfusion injury by antithrombin III after experimental pancreas transplantation. Am J Surg. 2005; 189(1):92-7. DOI: 10.1016/j.amjsurg.2004.03.017. View

16.

Sekimoto M, Takada T, Kawarada Y, Hirata K, Mayumi T, Yoshida M . JPN Guidelines for the management of acute pancreatitis: epidemiology, etiology, natural history, and outcome predictors in acute pancreatitis. J Hepatobiliary Pancreat Surg. 2006; 13(1):10-24. PMC: 2779368. DOI: 10.1007/s00534-005-1047-3. View

17.

Neoptolemos J, Kemppainen E, Mayer J, Fitzpatrick J, Raraty M, Slavin J . Early prediction of severity in acute pancreatitis by urinary trypsinogen activation peptide: a multicentre study. Lancet. 2000; 355(9219):1955-60. DOI: 10.1016/s0140-6736(00)02327-8. View

18.

Whitcomb D, Muddana V, Langmead C, Houghton Jr F, Guenther A, Eagon P . Angiopoietin-2, a regulator of vascular permeability in inflammation, is associated with persistent organ failure in patients with acute pancreatitis from the United States and Germany. Am J Gastroenterol. 2010; 105(10):2287-92. DOI: 10.1038/ajg.2010.183. View

19.

Takahashi N, Papachristou G, Schmit G, Chahal P, LeRoy A, Sarr M . CT findings of walled-off pancreatic necrosis (WOPN): differentiation from pseudocyst and prediction of outcome after endoscopic therapy. Eur Radiol. 2008; 18(11):2522-9. DOI: 10.1007/s00330-008-1039-1. View

20.

. UK guidelines for the management of acute pancreatitis. Gut. 2005; 54 Suppl 3:iii1-9. PMC: 1867800. DOI: 10.1136/gut.2004.057026. View