High-valent Organometallic Copper and Palladium in Catalysis

Overview

Journal Nature

Specialty Science

Date 2012 Apr 14

PMID 22498623

Citations 84

Authors

Amanda J Hickman

Melanie S Sanford

Affiliations

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Abstract

Copper and palladium catalysts are critically important in numerous commercial chemical processes. Improvements in the activity, selectivity and scope of these catalysts could drastically reduce the environmental impact, and increase the sustainability, of chemical reactions. One rapidly developing strategy for achieving these goals is to use 'high-valent' organometallic copper and palladium intermediates in catalysis. Here we describe recent advances involving both the fundamental chemistry and the applications of these high-valent metal complexes in numerous synthetically useful catalytic transformations.

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