Genotoxicity Studies Performed in the Ecuadorian Population
Overview
Affiliations
Genotoxicity studies in Ecuador have been carried out during the past two decades. The focuses of the research were mainly the area of environmental issues, where the populations have been accidentally exposed to contaminants and the area of occupational exposure of individuals at the workplace. This paper includes studies carried out in the population of the Amazon region, a zone known for its rich biodiversity as well as for the ecological damage caused by oil spills and chemical sprayings whose consequences continue to be controversial. Additionally, we show the results of studies comprised of individuals occupationally exposed to toxic agents in two very different settings: flower plantation workers exposed to pesticide mixtures and X-ray exposure of hospital workers. The results from these studies confirm that genotoxicity studies can help evaluate current conditions and prevent further damage in the populations exposed to contaminants. As such, they are evidence of the need for biomonitoring employers at risk, stricter law enforcement regarding the use of pesticides, and increasingly conscientious oil extraction activities.
De Novo Duplication of Chromosome 9p in a Female Infant: Phenotype and Genotype Correlation.
Leone P, Perez-Villa A, Yumiceba V, Hernandez M, Garcia-Cardenas J, Armendariz-Castillo I J Pediatr Genet. 2020; 9(1):69-75.
PMID: 31976149 PMC: 6976307. DOI: 10.1055/s-0039-1696970.
Paz-Y-Mino C, Yumiceba V, Moreta G, Paredes R, Ruiz M, Ocampo L Mol Genet Genomic Med. 2019; 8(2):e1087.
PMID: 31830383 PMC: 7005643. DOI: 10.1002/mgg3.1087.
Reategui-Zirena E, Stewart P, Whatley A, Chu-Koo F, Sotero-Solis V, Merino-Zegarra C Environ Monit Assess. 2013; 186(4):2171-84.
PMID: 24292871 DOI: 10.1007/s10661-013-3527-2.