An Experimental Model for Resistance Exercise in Rodents

Overview

Journal J Biomed Biotechnol

Specialty Biology

Date 2012 Apr 13

PMID 22496606

Citations 9

Authors

Humberto Nicastro

Nelo Eidy Zanchi

Claudia Ribeiro da Luz

Daniela Fojo Seixas Chaves

Antonio Herbert Lancha Jr

Affiliations

Soon will be listed here.

Abstract

This study aimed to develop an equipment and system of resistance exercise (RE), based on squat-type exercise for rodents, with control of training variables. We developed an operant conditioning system composed of sound, light and feeding devices that allowed optimized RE performance by the animal. With this system, it is not necessary to impose fasting or electric shock for the animal to perform the task proposed (muscle contraction). Furthermore, it is possible to perform muscle function tests in vivo within the context of the exercise proposed and control variables such as intensity, volume (sets and repetitions), and exercise session length, rest interval between sets and repetitions, and concentric strength. Based on the experiments conducted, we demonstrated that the model proposed is able to perform more specific control of other RE variables, especially rest interval between sets and repetitions, and encourages the animal to exercise through short-term energy restriction and "disturbing" stimulus that do not promote alterations in body weight. Therefore, despite experimental limitations, we believe that this RE apparatus is closer to the physiological context observed in humans.

Citing Articles

Sports activities and cardiovascular system change.

Stursova P, Budinska X, Novakova Z, Dobsak P, Babula P Physiol Res. 2024; 72(S5):S429-S444.

PMID: 38165749 PMC: 10861254. DOI: 10.33549/physiolres.935238.

Muscle Hypertrophy in a Newly Developed Resistance Exercise Model for Rats.

Al-Sarraf H, Mouihate A Front Physiol. 2022; 13:851789.

PMID: 35634153 PMC: 9136173. DOI: 10.3389/fphys.2022.851789.

Cardiovascular Adaptations Induced by Resistance Training in Animal Models.

Melo S, da Silva Junior N, Barauna V, Oliveira E Int J Med Sci. 2018; 15(4):403-410.

PMID: 29511376 PMC: 5835711. DOI: 10.7150/ijms.23150.

Inter-individual variation in adaptations to endurance and resistance exercise training: genetic approaches towards understanding a complex phenotype.

Vellers H, Kleeberger S, Lightfoot J Mamm Genome. 2018; 29(1-2):48-62.

PMID: 29356897 PMC: 5851699. DOI: 10.1007/s00335-017-9732-5.

Fasting: a major limitation for resistance exercise training effects in rodents.

das Neves W, de Oliveira L, Silva R, Alves C, Lancha Jr A Braz J Med Biol Res. 2017; 51(1):e5427.

PMID: 29185588 PMC: 5685054. DOI: 10.1590/1414-431X20175427.

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