Reliability of RTVue, Visante, and Slit-lamp Adapted Ultrasonic Pachymetry for Central Corneal Thickness Measurement

Overview

Journal Yonsei Med J

Specialty General Medicine

Date 2012 Apr 6

PMID 22477010

Citations 5

Authors

Jin Pyo Hong

Sang Min Nam

Tae-Im Kim

Kyoung Yul Seo

Sang Yeop Lee

Alessandro Meduri

Eung Kweon Kim

Affiliations

Soon will be listed here.

Abstract

Purpose: To evaluate reliability of Fourier-domain optical coherence tomography (OCT) (RTVue), time-domain OCT (Visante), and slit-lamp adapted ultrasonic pachymetry (SL-US) in the measurement of central corneal thickness (CCT).

Materials And Methods: Thirty healthy volunteers visited our clinic 3 times and fifty eyes were measured by one physician. RTVue and Visante were randomly performed, and then SL-US, in which the ultrasound probe was inserted into the Goldmann tonometry mount, was done. During the second visit, each measurement was repeated 3 times. Measurements on the second visit were averaged, and agreement among the instruments was investigated with Bland-Altman plots.

Results: RTVue showed smaller repeatability coefficient than Visante and SL-US (4.7, 8.3, and 7.7 μm, respectively). Intersession reproducibility of RTVue and Visante was worse than their repeatability. CCT of RTVue was estimated to be maximally different by 11.8 μm from CCT of Visante and 8.8 μm from CCT of SL-US. The repeatability coefficient of SL-US was 7.7 μm and its reproducibility was similar to the repeatability.

Conclusion: CCT measured by RTVue showed good reliability and generally agreed with Visante and SL-US. SL-US was as reliable as triple touching conventional US even with a single touch on the cornea.

Citing Articles

Repeatability and reproducibility of a new spectral-domain optical coherence tomography biometer and agreement with swept-source optical coherence tomography based biometer.

Li X, Lei C, Ning R, Liu L, Chen A, Yang X Eye Vis (Lond). 2025; 12(1):6.

PMID: 39891211 PMC: 11786401. DOI: 10.1186/s40662-024-00422-0.

Repeatability and agreement of AOCT-1000 M, RTVue XR and IOL master 500 in measuring corneal thickness mapping and axial length applying principle of optical coherence tomography.

Ni H, Xu S, Tian L, Mao J, Li J, Lin N BMC Med Imaging. 2023; 23(1):194.

PMID: 37990166 PMC: 10664477. DOI: 10.1186/s12880-023-01147-7.

Measurement and Analysis of Central Corneal Thickness at Different Postnatal Stages in Chinese Premature Infants.

Liu C, Wu H, Lao J, Wu S, Xu X, Lv Z J Ophthalmol. 2020; 2020:7313909.

PMID: 33014441 PMC: 7519199. DOI: 10.1155/2020/7313909.

Repeatability assessment of anterior segment biometric measurements under accommodative and nonaccommodative conditions using an anterior segment OCT.

Martinez-Albert N, Esteve-Taboada J, Montes-Mico R Graefes Arch Clin Exp Ophthalmol. 2017; 256(1):113-123.

PMID: 29098383 DOI: 10.1007/s00417-017-3832-5.

Repeatability of corneal epithelial thickness measurements using Fourier-domain optical coherence tomography in normal and post-LASIK eyes.

Ma X, Wang L, Koch D Cornea. 2013; 32(12):1544-8.

PMID: 24145634 PMC: 4038409. DOI: 10.1097/ICO.0b013e3182a7f39d.

References

Amano S, Honda N, Amano Y, Yamagami S, Miyai T, Samejima T . Comparison of central corneal thickness measurements by rotating Scheimpflug camera, ultrasonic pachymetry, and scanning-slit corneal topography. Ophthalmology. 2006; 113(6):937-41. DOI: 10.1016/j.ophtha.2006.01.063. View

Kaluzny B, Kaluzy B, Kaluzny J, Szkulmowska A, Gorczynska I, Szkulmowski M . Spectral optical coherence tomography: a novel technique for cornea imaging. Cornea. 2006; 25(8):960-5. DOI: 10.1097/01.ico.0000224644.81719.59. View

Nam S, Im C, Lee H, Kim E, Kim T, Seo K . Accuracy of RTVue optical coherence tomography, Pentacam, and ultrasonic pachymetry for the measurement of central corneal thickness. Ophthalmology. 2010; 117(11):2096-103. DOI: 10.1016/j.ophtha.2010.03.002. View

Zhao P, Wong T, Wong W, Saw S, Aung T . Comparison of central corneal thickness measurements by visante anterior segment optical coherence tomography with ultrasound pachymetry. Am J Ophthalmol. 2007; 143(6):1047-9. DOI: 10.1016/j.ajo.2007.01.050. View

ODonnell C, Maldonado-Codina C . Agreement and repeatability of central thickness measurement in normal corneas using ultrasound pachymetry and the OCULUS Pentacam. Cornea. 2005; 24(8):920-4. DOI: 10.1097/01.ico.0000157422.01146.e9. View

Prydal J, Artal P, Woon H, CAMPBELL F . Study of human precorneal tear film thickness and structure using laser interferometry. Invest Ophthalmol Vis Sci. 1992; 33(6):2006-11. View

Leem H, Lee K, Shin K . Central corneal thickness and corneal endothelial cell changes caused by contact lens use in diabetic patients. Yonsei Med J. 2011; 52(2):322-5. PMC: 3051206. DOI: 10.3349/ymj.2011.52.2.322. View

Mohamed S, Lee G, Rao S, Wong A, Cheng A, Li E . Repeatability and reproducibility of pachymetric mapping with Visante anterior segment-optical coherence tomography. Invest Ophthalmol Vis Sci. 2007; 48(12):5499-504. DOI: 10.1167/iovs.07-0591. View

Huang D, Swanson E, Lin C, Schuman J, Stinson W, Chang W . Optical coherence tomography. Science. 1991; 254(5035):1178-81. PMC: 4638169. DOI: 10.1126/science.1957169. View

10.

Bland J, Altman D . Measurement error. BMJ. 1996; 313(7059):744. PMC: 2352101. DOI: 10.1136/bmj.313.7059.744. View

11.

Realini T, Lovelace K . Measuring central corneal thickness with ultrasound pachymetry. Optom Vis Sci. 2003; 80(6):437-9. DOI: 10.1097/00006324-200306000-00009. View

12.

Prakash G, Agarwal A, Jacob S, Kumar D, Agarwal A, Banerjee R . Comparison of fourier-domain and time-domain optical coherence tomography for assessment of corneal thickness and intersession repeatability. Am J Ophthalmol. 2009; 148(2):282-290.e2. DOI: 10.1016/j.ajo.2009.03.012. View

13.

Lackner B, Schmidinger G, Pieh S, Funovics M, Skorpik C . Repeatability and reproducibility of central corneal thickness measurement with Pentacam, Orbscan, and ultrasound. Optom Vis Sci. 2005; 82(10):892-9. DOI: 10.1097/01.opx.0000180817.46312.0a. View

14.

Muscat S, McKay N, Parks S, Kemp E, Keating D . Repeatability and reproducibility of corneal thickness measurements by optical coherence tomography. Invest Ophthalmol Vis Sci. 2002; 43(6):1791-5. View

15.

Huang J, Pekmezci M, Yaplee S, Lin S . Intra-examiner repeatability and agreement of corneal pachymetry map measurement by time-domain and Fourier-domain optical coherence tomography. Graefes Arch Clin Exp Ophthalmol. 2010; 248(11):1647-56. DOI: 10.1007/s00417-010-1360-7. View

16.

Bland J, Altman D . Agreement between methods of measurement with multiple observations per individual. J Biopharm Stat. 2007; 17(4):571-82. DOI: 10.1080/10543400701329422. View

17.

Bland J, Altman D . Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986; 1(8476):307-10. View

18.

Nam S, Lee H, Kim E, Seo K . Comparison of corneal thickness after the instillation of topical anesthetics: proparacaine versus oxybuprocaine. Cornea. 2005; 25(1):51-4. DOI: 10.1097/01.ico.0000179929.97651.59. View

19.

Chen S, Huang J, Wen D, Chen W, Huang D, Wang Q . Measurement of central corneal thickness by high-resolution Scheimpflug imaging, Fourier-domain optical coherence tomography and ultrasound pachymetry. Acta Ophthalmol. 2010; 90(5):449-55. DOI: 10.1111/j.1755-3768.2010.01947.x. View

20.

Doughty M, Zaman M . Human corneal thickness and its impact on intraocular pressure measures: a review and meta-analysis approach. Surv Ophthalmol. 2000; 44(5):367-408. DOI: 10.1016/s0039-6257(00)00110-7. View