Neurological Disorders in Primary Sjögren's Syndrome

Overview

Journal Autoimmune Dis

Publisher Wiley

Date 2012 Apr 5

PMID 22474573

Citations 36

Authors

Gabriel J Tobon

Jacques-Olivier Pers

Valerie Devauchelle-Pensec

Pierre Youinou

Affiliations

Soon will be listed here.

Abstract

Sjögren's syndrome is an autoimmune disease characterized by an autoimmune exocrinopathy involving mainly salivary and lacrimal glands. The histopathological hallmark is periductal lymphocytic infiltration of the exocrine glands, resulting in loss of their secretory function. Several systemic manifestations may be found in patients with Sjögren's syndrome including neurological disorders. Neurological involvement ranges from 0 to 70% among various series and may present with central nervous system and/or peripheral nervous system involvement. This paper endeavors to review the main clinical neurological manifestations in Sjögren syndrome, the physiopathology, and their therapeutic response.

Citing Articles

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