Torsade De Pointes and Persistent QTc Prolongation After Intravenous Amiodarone

Overview

Journal Case Rep Med

Publisher Wiley

Specialty General Medicine

Date 2012 Apr 5

PMID 22474460

Citations 3

Authors

Anna P Kotsia

Georgios Dimitriadis

Giannis G Baltogiannis

Theofilos M Kolettis

Affiliations

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Abstract

We report a case of torsade de pointes after intravenous amiodarone and concurrent hypokalemia. Despite treatment cessation and correction of electrolyte abnormalities, excessive QTc prolongation was noted, which persisted for 14 days. This prolonged course for QTc normalization may be attributed to the high rate of amiodarone loading and concurrent electrolyte disturbances coupled with possible underlying individual variability in pharmacokinetics.

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