Effect of Ovarian Stimulation and Oocyte Retrieval on Reproductive Outcome in Oocyte Donors

Objective: To assess whether there is an increased risk of infertility in women that have previously undergone ovarian stimulation and oocyte retrieval for oocyte donation.

Design: Cross-sectional survey.

Setting: Tertiary referral center.

Patient(s): A total of 194 past oocyte donors.

Intervention(s): Telephone questionnaire.

Main Outcome Measure(s): Incidence of infertility after oocyte donation.

Result(s): Of the women who indicated having pursued conception after oocyte donation, 95% (57/60) became pregnant unassisted. Before oocyte donation, 41 women in this cohort had already been trying to conceive, of which 38 had delivered a child and 3 (7.3%) had needed infertility treatment.

Conclusion(s): The data suggest that oocyte donation does not affect short-term reproductive health.