Troponin-positive Chest Pain with Unobstructed Coronary Arteries: Definitive Differential Diagnosis Using Cardiac MRI

Overview

Journal Br J Radiol

Publisher Oxford University Press

Specialty Radiology

Date 2012 Mar 30

PMID 22457316

Citations 11

Authors

M Mahmoudi

S Harden

N Abid

C Peebles

Z Nicholas

T Jones

D McKenzie

N Curzen

Affiliations

Soon will be listed here.

Abstract

Objective: The purpose of this study was to assess the outcome of cardiac MRI (CMRI) with late gadolinium enhancement (LGE) at outpatient follow-up in a consecutive series of patients with troponin-positive chest pain but unobstructed coronary arteries at the index admission.

Methods: The study group comprised 91 consecutive patients who presented to our institution with cardiac chest pain, elevated troponin I and unobstructed coronary arteries on coronary angiography. All patients underwent an outpatient CMRI with LGE imaging in order to establish a definitive diagnosis.

Results: The average time from coronary angiography to LGE-CMRI was 2 months. 73% of patients had no abnormality on their LGE-CMRI, 16% of patients had patchy late enhancement consistent with myocarditis and 11% had focal subendocardial or full thickness late enhancement consistent with myocardial infarction. There were no deaths in this cohort during a mean follow-up of 21 months.

Conclusion: LGE-CMRI is a useful tool for establishing whether such patients have definitive evidence of non-ST-segment elevation myocardial infarction (NSTEMI), and can make an important contribution to the long-term management strategy of these patients as an inappropriate diagnosis of NSTEMI carries important medical, social and financial implications.

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