ClusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

Overview

Journal OMICS

Specialties Biology
Molecular Biology

Date 2012 Mar 30

PMID 22455463

Citations 15569

Authors

Guangchuang Yu

Li-Gen Wang

Yanyan Han

Qing-Yu He

Affiliations

Soon will be listed here.

Abstract

Increasing quantitative data generated from transcriptomics and proteomics require integrative strategies for analysis. Here, we present an R package, clusterProfiler that automates the process of biological-term classification and the enrichment analysis of gene clusters. The analysis module and visualization module were combined into a reusable workflow. Currently, clusterProfiler supports three species, including humans, mice, and yeast. Methods provided in this package can be easily extended to other species and ontologies. The clusterProfiler package is released under Artistic-2.0 License within Bioconductor project. The source code and vignette are freely available at http://bioconductor.org/packages/release/bioc/html/clusterProfiler.html.

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