Approach to and Treatment of Goiters
Overview
Affiliations
The main causes of simple diffuse goiter (SDG) and multinodular goiter (MNG) are iodine deficiency, increase in serum thyroid-stimulating hormone (TSH) level, natural goitrogens, smoking, chronic malnutrition, and lack of selenium, iron, and zinc. Increasing evidence suggests that heredity is equally important. Treatment of SDG and MNG still focuses on L-thyroxine-suppressive therapy surgery. Radioiodine alone or preceded by recombinant human TSH stimulation is widely used in Europe and other countries. Each of these therapeutic options has advantages and disadvantages, with acute and long-term side effects.
Langerhans Cell Histiocytosis Presenting as Anterior Neck Mass in a Child: A Case Report.
Betansos K, Cachero M, Santos C, Fernandez E, Mabulac M, Abad L J ASEAN Fed Endocr Soc. 2023; 38(2):149-153.
PMID: 38045678 PMC: 10692419. DOI: 10.15605/jafes.038.02.15.
Non-Toxic Multinodular Goiter: From Etiopathogenesis to Treatment.
Unlu M, Kostek M, Aygun N, Isgor A, Uludag M Sisli Etfal Hastan Tıp Bul. 2022; 56(1):21-40.
PMID: 35515961 PMC: 9040296. DOI: 10.14744/SEMB.2022.56514.
Recombinant human thyrotropin (rhTSH)-aided radioiodine treatment for non-toxic multinodular goitre.
Huo Y, Xie J, Chen S, Wang H, Ma C Cochrane Database Syst Rev. 2021; 12:CD010622.
PMID: 34961921 PMC: 8712889. DOI: 10.1002/14651858.CD010622.pub2.
Garcia-Alva R, Bobadilla-Rosado L, Arzola L, Escobar-Preciado M, Anaya-Ayala J, Hinojosa C Int J Surg Case Rep. 2018; 53:17-20.
PMID: 30366171 PMC: 6205148. DOI: 10.1016/j.ijscr.2018.10.019.
Aghajanzadeh M, Asgary M, Mohammadi F, Darvishi H, Safarpour Y J Family Med Prim Care. 2018; 7(1):224-229.
PMID: 29915764 PMC: 5958574. DOI: 10.4103/jfmpc.jfmpc_286_17.