» Articles » PMID: 22442534

Fibroids, Infertility and Laparoscopic Myomectomy

Overview
Specialty Gastroenterology
Date 2012 Mar 24
PMID 22442534
Citations 13
Authors
Affiliations
Soon will be listed here.
Abstract

Objective: To review the literature and summarize the available evidence about the relationship of fibroids with infertility and to review the role of laparoscopic myomectomy in infertility.

Materials And Methods: Medline, PubMed, and Cochrane Databases were searched for articles published between 1980 and 2010.

Results: Fertility outcomes are decreased in women with submucosal fibroids, and myomectomy is of value. Subserosal fibroids do not affect fertility outcomes, and removal may not confer benefit. Intramural fibroids appear to decrease fertility, but the results of therapy are unclear. Although pregnancy rates for women with leiomyomata, managed endoscopically, are similar to those after laparotomy, there is a risk of uterine rupture. The risk is essentially unknown. Finally, the risk of recurrence seems higher after laparoscopic myomectomy compared to laparotomy.

Conclusions: Laparoscopic myomectomy, when performed by an experienced surgeon, can be considered a safe technique, with an extremely low failure rate and good results in terms of the outcome of pregnancy.

Citing Articles

Managing Primary Infertility in a Woman With Uterine Fibroids Utilizing Myomectomy and In Vitro Maturation (IVM) of Oocytes.

Bondare R, Shrivastava J, Choudhary N, Tyagi P, Ulhe S, More A Cureus. 2024; 16(4):e59257.

PMID: 38813276 PMC: 11134482. DOI: 10.7759/cureus.59257.


Uterine fibroids - Causes, impact, treatment, and lens to the African perspective.

Sefah N, Ndebele S, Prince L, Korasare E, Agbleke M, Nkansah A Front Pharmacol. 2023; 13:1045783.

PMID: 36703761 PMC: 9871264. DOI: 10.3389/fphar.2022.1045783.


Ruptured ectopic molar pregnancy and ruptured uterine fibroid: a challenging rare diagnosis.

Tanudisastro M, Chatterjee R, Anderson L, Smirnova S BMJ Case Rep. 2023; 16(1.

PMID: 36653040 PMC: 9853148. DOI: 10.1136/bcr-2022-251045.


Concurrent gestational trophoblastic neoplasia and large uterine fibroid in a nullipara - Case report.

Anwar R, Tjandraprawira K, Irawan B Ann Med Surg (Lond). 2022; 77:103659.

PMID: 35638016 PMC: 9142663. DOI: 10.1016/j.amsu.2022.103659.


A Systematic Review of Minimally Invasive Treatments for Uterine Fibroid-Related Bleeding.

Zhang J, Go V, Friel Blanck J, Singh B Reprod Sci. 2021; 29(10):2786-2809.

PMID: 34480321 DOI: 10.1007/s43032-021-00722-z.


References
1.
Pelosi 3rd M, Pelosi M . Spontaneous uterine rupture at thirty-three weeks subsequent to previous superficial laparoscopic myomectomy. Am J Obstet Gynecol. 1998; 177(6):1547-9. DOI: 10.1016/s0002-9378(97)70110-8. View

2.
Dubuisson J, Fauconnier A, Deffarges J, Norgaard C, Kreiker G, Chapron C . Pregnancy outcome and deliveries following laparoscopic myomectomy. Hum Reprod. 2000; 15(4):869-73. DOI: 10.1093/humrep/15.4.869. View

3.
Holub Z . [Laparoscopic myomectomy: indications and limits]. Ceska Gynekol. 2007; 72(1):64-8. View

4.
Goldberg J, Pereira L . Pregnancy outcomes following treatment for fibroids: uterine fibroid embolization versus laparoscopic myomectomy. Curr Opin Obstet Gynecol. 2006; 18(4):402-6. DOI: 10.1097/01.gco.0000233934.13684.cb. View

5.
Griffiths A, DAngelo A, Amso N . Surgical treatment of fibroids for subfertility. Cochrane Database Syst Rev. 2006; (3):CD003857. DOI: 10.1002/14651858.CD003857.pub2. View