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Male Gender Bias in Autism and Pediatric Autoimmunity

Overview
Journal Autism Res
Specialty Psychiatry
Date 2012 Mar 21
PMID 22431266
Citations 5
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Abstract

Male bias in both autism and pediatric autoimmune disease is thought to involve hormonal perturbations in pregnancy or early childhood in the context of genetic control. These early molecular events, at a time of rapid development, are intimately linked to concurrent development in the brain and immune system. It is suggested here that these early regulatory events may overlap between autism and autoimmunity in determining male sex bias and may provide evidence of an etiological link among autism, immune dysregulation, and autoimmune disease.

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