Drug Kinetics and Artificial Kidneys

Overview

Journal Clin Pharmacokinet

Specialty Pharmacology

Date 1977 Nov 1

PMID 22417

Citations 26

Authors

T B Gibson

H A NELSON

Affiliations

Soon will be listed here.

Abstract

The factors affecting solute movement across the membrane during haemodialysis are well understood. Likewise the mathematics of drug kinetics are well described. However, studies of the effects of artificial kidneys on drug kinetics have often been limited by a lack of attention to proper methods of calculating solute clearance by the artificial kidney.

Citing Articles

Effect of severe renal failure and haemodialysis on the pharmacokinetics of levosimendan and its metabolites.

Puttonen J, Kantele S, Kivikko M, Hakkinen S, Harjola V, Koskinen P Clin Pharmacokinet. 2007; 46(3):235-46.

PMID: 17328582 DOI: 10.2165/00003088-200746030-00004.

The effect of haemodialysis on the pharmacokinetics of perindoprilat after long-term perindopril.

Guerin A, Resplandy G, Marchais S, Taillard F, London G Eur J Clin Pharmacol. 1993; 44(2):183-7.

PMID: 8453964 DOI: 10.1007/BF00315478.

Drug dosage in end-stage renal disease (ESRD) patients undergoing haemodialysis. A predictive study based on a microcomputer program.

Sanchez Burson J, Dominguez-Gil A Clin Pharmacokinet. 1993; 25(3):243-57.

PMID: 8222463 DOI: 10.2165/00003088-199325030-00007.

The effect of impaired renal function on the plasma concentration and urinary excretion of metoprolol metabolites.

Hoffmann K, Regardh C, Aurell M, ERVIK M, Jordo L Clin Pharmacokinet. 1980; 5(2):181-91.

PMID: 7363533 DOI: 10.2165/00003088-198005020-00005.

Dosage adjustment in renal insufficiency.

Mawer G Br J Clin Pharmacol. 1982; 13(2):145-53.

PMID: 7059411 PMC: 1402007. DOI: 10.1111/j.1365-2125.1982.tb01349.x.

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