Insomnia in Patients with COPD

Overview

Journal Sleep

Publisher Oxford University Press

Specialty Psychiatry

Date 2012 Mar 2

PMID 22379243

Citations 46

Authors

Rohit Budhiraja

Sairam Parthasarathy

Pooja Budhiraja

Michael P Habib

Christopher Wendel

Stuart F Quan

Affiliations

Soon will be listed here.

Abstract

Study Objectives: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality and may frequently be associated with sleep disturbances. However, the correlates of insomnia in COPD patients have not been well characterized. The aim of the current study was to describe the prevalence of insomnia disorder in COPD and to elucidate the demographic and clinical characteristics of COPD patients that are associated with insomnia.

Design: Cross-sectional study.

Setting: Clinic-based sample from an academic hospital.

Participants: Patients with stable COPD.

Measurements: An interviewer-conducted survey was administered to 183 participants with COPD. Seventy-two of these participants (30 with and 42 without insomnia) maintained a sleep diary and underwent actigraphy for 7 days.

Results: Insomnia (chronic sleep disturbance associated with impaired daytime functioning) was present in 27.3% of participants. Current tobacco users (odds ratio (OR), 2.13) and those with frequent sadness/anxiety (OR, 3.57) had higher odds, but oxygen use was associated with lower odds (OR, 0.35) of insomnia. Patients with insomnia had worse quality of life and a higher prevalence of daytime sleepiness. Actigraphy revealed shorter sleep duration and lower sleep efficiency, and a sleep diary revealed worse self-reported sleep quality in participants with insomnia.

Conclusion: Insomnia disorder is highly prevalent in patients with COPD; current tobacco use and sadness/anxiety are associated with a higher prevalence, and oxygen use with a lower prevalence of insomnia; patients with insomnia have poorer quality of life and increased daytime sleepiness; and insomnia is associated with worse objective sleep quality.

Citing Articles

The Effect of Sleep Impairment, as Assessed by the CASIS Questionnaire, in Patients with Chronic Obstructive Pulmonary Disease on Disease Severity and Physical and Mental Health: A Cross-Sectional Study in Primary Care.

Bouloukaki I, Christodoulakis A, Margetaki K, Tsiligianni I Biomedicines. 2024; 12(8).

PMID: 39200109 PMC: 11351845. DOI: 10.3390/biomedicines12081644.

Sex-differences in COPD: from biological mechanisms to therapeutic considerations.

Milne K, Mitchell R, Ferguson O, Hind A, Guenette J Front Med (Lausanne). 2024; 11:1289259.

PMID: 38572156 PMC: 10989064. DOI: 10.3389/fmed.2024.1289259.

Exploring the Link between Social Support and Patient-Reported Outcomes in Chronic Obstructive Pulmonary Disease Patients: A Cross-Sectional Study in Primary Care.

Bouloukaki I, Christodoulakis A, Margetaki K, Aravantinou Karlatou A, Tsiligianni I Healthcare (Basel). 2024; 12(5).

PMID: 38470655 PMC: 10930953. DOI: 10.3390/healthcare12050544.

Comorbidities in COPD: Current and Future Treatment Challenges.

Mariniello D, DAgnano V, Cennamo D, Conte S, Quarcio G, Notizia L J Clin Med. 2024; 13(3).

PMID: 38337438 PMC: 10856710. DOI: 10.3390/jcm13030743.

Association Between Hypnotic Use and All-Cause Mortality in Patients with Chronic Obstructive Pulmonary Disease and Insomnia.

El-Solh A, Lawson Y, Wilding G Int J Chron Obstruct Pulmon Dis. 2023; 18:2393-2404.

PMID: 37942297 PMC: 10629458. DOI: 10.2147/COPD.S430609.

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