[Comorbidities and Psoriasis. Impact on Clinical Practice]

Overview

Journal Hautarzt

Specialty Dermatology

Date 2012 Mar 1

PMID 22373901

Citations 4

Authors

S Gerdes

U Mrowietz

Affiliations

Soon will be listed here.

Abstract

Psoriasis is a genetically determined, chronic inflammatory systemic disease. Besides skin symptoms, patients with moderate to severe forms of psoriasis show an association with other diseases, referred to as comorbidities. Metabolic disorders (e.g. diabetes mellitus, insulin resistance, dyslipidemia mainly in obese patients) and cardiovascular diseases (e.g. arterial hypertension, coronary artery disease, myocardial infarction and stroke) are of importance as they can increase patients' mortality. In addition, psychiatric diseases are more frequent in psoriasis patients and influence the therapeutic approach. The dermatologist in most cases is the primarily consulted physician for patients with psoriasis and therefore plays the role as a gatekeeper managing therapy. He is responsible for the early diagnosis of comorbidities and insuring their appropriate management. The anti-psoriatic treatment has to be adapted to existing comorbidities and their systemic treatments. The following article provides information on psoriatic comorbidities and their consequences for daily practice.

Citing Articles

Psoriasis in obesity: comparison of serum levels of leptin and adiponectin in obese subjects - cases and controls.

Bavoso N, Pinto J, Soares M, Diniz M, Teixeira Junior A An Bras Dermatol. 2019; 94(2):192-197.

PMID: 31090824 PMC: 6486065. DOI: 10.1590/abd1806-4841.20197716.

[Depression and anxiety disorders among psoriasis patients: protective and exacerbating factors].

Bangemann K, Schulz W, Wohlleben J, Weyergraf A, Snitjer I, Werfel T Hautarzt. 2014; 65(12):1056-61.

PMID: 25376619 DOI: 10.1007/s00105-014-3513-9.

Psoriasis and psychiatric morbidity: a profile from a tertiary care centre of eastern India.

Sarkar S, Sarkar A, Saha R, Sarkar T J Family Med Prim Care. 2014; 3(1):29-32.

PMID: 24791233 PMC: 4005196. DOI: 10.4103/2249-4863.130267.

[Does the risk of cardiovascular complications decrease in psoriatic patients receiving systemic therapy?].

Glaser R, Gerdes S Hautarzt. 2012; 64(1):63-4.

PMID: 23212680 DOI: 10.1007/s00105-012-2522-9.

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