Evaluation of Rheological Properties and Swelling Behaviour of Sonicated Scleroglucan Samples

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2012 Feb 28

PMID 22367024

Citations 2

Authors

Siddique Akber Ansari

Pietro Matricardi

Chiara Di Meo

Franco Alhaique

Tommasina Coviello

Affiliations

Soon will be listed here.

Abstract

Scleroglucan is a natural polysaccharide that has been proposed for various applications. However there is no investigation on its property variations when the molecular weight of this polymer is reduced. Scleroglucan was sonicated at two different polymer concentrations for different periods of time and the effect of sonication was investigated with respect to molecular weight variations and rheological properties. Molar mass, estimated by viscometric measurements, was drastically reduced already after a sonication for a few min. Sonicated samples were used for the preparation of gels in the presence of borate ions. The effect of borax on the new samples was investigated by recording the mechanical spectra and the flow curves. A comparison with the system prepared with the dialysed polymer was also carried out. The anisotropic elongation, observed with tablets of scleroglucan and borax, was remarkably reduced when the sonicated samples were used for the preparation of the gels.

Citing Articles

The Influence of pH on the Scleroglucan and Scleroglucan/Borax Systems.

Mazzuca C, Bocchinfuso G, Palleschi A, Conflitti P, Grassi M, Di Meo C Molecules. 2017; 22(3).

PMID: 28282944 PMC: 6155179. DOI: 10.3390/molecules22030435.

Sonication-based improvement of the physicochemical properties of Guar Gum as a potential substrate for modified drug delivery systems.

Ansari S, Matricardi P, Cencetti C, Di Meo C, Carafa M, Mazzuca C Biomed Res Int. 2013; 2013:985259.

PMID: 23984426 PMC: 3747617. DOI: 10.1155/2013/985259.

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