Long-term Prognosis of Patients with Cardiac Syndrome X: a Review

Overview

Journal Neth Heart J

Specialty Cardiology & Vascular Diseases

Date 2012 Feb 24

PMID 22359248

Citations 10

Authors

I A C Vermeltfoort

G J J Teule

A B van Dijk

H J Muntinga

P G H M Raijmakers

Affiliations

Soon will be listed here.

Abstract

Aims: Follow-up studies of patients with cardiac syndrome X (CSX) generally report good prognosis. However, some recent studies report an adverse outcome for women.

Methods And Results: Structured literature search and meta-analysis for studies regarding prognosis of cardiac syndrome X patients. We identified 85 studies, ultimately selecting 16 for inclusion. Meta-analysis yielded a pooled major cardiac event percentage of 1.5% per 5 years and a pooled vascular event percentage of 4.8% per 5 years (n = 16 studies, n = 1694 patients). Fourteen studies reported upon the recurrence rate of angina pectoris: the pooled percentage of angina recurrence was 55% (n = 1336 patients).

Conclusion: The present review of recent archival literature demonstrates an overall major cardiac event rate of 1.5% per 5 years. Although this is an excellent prognosis for CSX patients, the quality of life is impaired because of the high recurrence rate of angina pectoris (55%).

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