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Natural Sesquiterpenoids As Cytotoxic Anticancer Agents

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Specialty Chemistry
Date 2012 Feb 23
PMID 22353224
Citations 16
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Abstract

Sesquiterpenoids are a group of naturally occurring 15-carbon isoprenoid compounds that are mainly found in higher plants, microorganism and marine life. Many of them provided encouraging leads for chemotherapeutics. In this review, the sesquiterpenoids are classified according to the ring numbering system and the functional groups presented in the core structures as acyclic, mono-, bi-, and tricyclic derivatives, and a current overview of sesquiterpenoids as potential cytotoxic anticancer agents is provided.

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