Assessment of Left Ventricular Diastolic Function by MR: Why, How and when

Overview

Journal Insights Imaging

Publisher Springer

Specialty Radiology

Date 2012 Feb 21

PMID 22347914

Citations 5

Authors

Ricardo Duarte

Gabriel Fernandez

Affiliations

Soon will be listed here.

Abstract

Cardiovascular magnetic resonance (CMR), a valuable non-invasive technique for the evaluation of the cardiovascular system, has already been accepted as the "gold standard" for the assessment of systolic function. The assessment of diastolic function is important not only for diagnosis purposes, but also in terms of prognosis. ECG-triggering phase-contrast (PC) CMR allows the routine assessment of diastolic function by measuring the transmitral and pulmonary venous flow with high accuracy and reproducibility, using morphological and quantitative parameters similar to those obtained by transthoracic echocardiography, which are so familiar to general cardiologists. Therefore, the increasing role of CMR in the assessment of the cardiovascular system requires a greater awareness and knowledge of this condition by radiologists. The aim of this study is to review the main mechanisms and common causes of left ventricle diastolic dysfunction, provide a practical approach for the assessment of LV diastolic function and illustrate the different degrees of diastolic dysfunction.

Citing Articles

Serum metabolite signatures of cardiac function and morphology in individuals from a population-based cohort.

Maushagen J, Addin N, Schuppert C, Ward-Caviness C, Nattenmuller J, Adamski J Biomark Res. 2024; 12(1):31.

PMID: 38444025 PMC: 10916302. DOI: 10.1186/s40364-024-00578-w.

Assessment of diastolic dysfunction: comparison of different cardiovascular magnetic resonance techniques.

Kermer J, Traber J, Utz W, Hennig P, Menza M, Jung B ESC Heart Fail. 2020; 7(5):2637-2649.

PMID: 32686332 PMC: 7524101. DOI: 10.1002/ehf2.12846.

Assessment of diastolic function and atrial remodeling by MRI - validation and correlation with echocardiography and filling pressure.

Seemann F, Baldassarre L, Llanos-Chea F, Gonzales R, Grunseich K, Hu C Physiol Rep. 2018; 6(17):e13828.

PMID: 30187654 PMC: 6125607. DOI: 10.14814/phy2.13828.

Left ventricular structure and diastolic function by cardiac magnetic resonance imaging in hypertrophic cardiomyopathy.

Chacko B, Karur G, Connelly K, Yan R, Kirpalani A, Wald R Indian Heart J. 2018; 70(1):75-81.

PMID: 29455792 PMC: 5902823. DOI: 10.1016/j.ihj.2016.12.021.

Left atrial dysfunction in type 2 diabetes mellitus: insights from cardiac MRI.

Graca B, Ferreira M, Donato P, Gomes L, Castelo-Branco M, Caseiro-Alves F Eur Radiol. 2014; 24(11):2669-76.

PMID: 25027838 DOI: 10.1007/s00330-014-3299-2.

References

Galderisi M . Diastolic dysfunction and diastolic heart failure: diagnostic, prognostic and therapeutic aspects. Cardiovasc Ultrasound. 2005; 3:9. PMC: 1087861. DOI: 10.1186/1476-7120-3-9. View

Vasan R, Benjamin E . Diastolic heart failure--no time to relax. N Engl J Med. 2001; 344(1):56-9. DOI: 10.1056/NEJM200101043440111. View

Sakuma H, Kawada N, Kubo H, Nishide Y, Takano K, Kato N . Effect of breath holding on blood flow measurement using fast velocity encoded cine MRI. Magn Reson Med. 2001; 45(2):346-8. DOI: 10.1002/1522-2594(200102)45:2<346::aid-mrm1044>3.0.co;2-i. View

Caruthers S, Lin S, Brown P, Watkins M, Williams T, Lehr K . Practical value of cardiac magnetic resonance imaging for clinical quantification of aortic valve stenosis: comparison with echocardiography. Circulation. 2003; 108(18):2236-43. DOI: 10.1161/01.CIR.0000095268.47282.A1. View

Lee V, Spritzer C, Carroll B, Pool L, Bernstein M, Heinle S . Flow quantification using fast cine phase-contrast MR imaging, conventional cine phase-contrast MR imaging, and Doppler sonography: in vitro and in vivo validation. AJR Am J Roentgenol. 1997; 169(4):1125-31. DOI: 10.2214/ajr.169.4.9308476. View

Wheeldon N, Clarkson P, MacDonald T . Diastolic heart failure. Eur Heart J. 1994; 15(12):1689-97. DOI: 10.1093/oxfordjournals.eurheartj.a060453. View

Aurigemma G, Gottdiener J, Shemanski L, GARDIN J, Kitzman D . Predictive value of systolic and diastolic function for incident congestive heart failure in the elderly: the cardiovascular health study. J Am Coll Cardiol. 2001; 37(4):1042-8. DOI: 10.1016/s0735-1097(01)01110-x. View

Katz A, Zile M . New molecular mechanism in diastolic heart failure. Circulation. 2006; 113(16):1922-5. DOI: 10.1161/CIRCULATIONAHA.106.620765. View

Senni M, Tribouilloy C, Rodeheffer R, Jacobsen S, Evans J, Bailey K . Congestive heart failure in the community: a study of all incident cases in Olmsted County, Minnesota, in 1991. Circulation. 1998; 98(21):2282-9. DOI: 10.1161/01.cir.98.21.2282. View

10.

Chatzimavroudis G, Oshinski J, FRANCH R, Walker P, Yoganathan A, Pettigrew R . Evaluation of the precision of magnetic resonance phase velocity mapping for blood flow measurements. J Cardiovasc Magn Reson. 2001; 3(1):11-9. DOI: 10.1081/jcmr-100000142. View

11.

Bellenger N, Burgess M, Ray S, Lahiri A, Coats A, Cleland J . Comparison of left ventricular ejection fraction and volumes in heart failure by echocardiography, radionuclide ventriculography and cardiovascular magnetic resonance; are they interchangeable?. Eur Heart J. 2000; 21(16):1387-96. DOI: 10.1053/euhj.2000.2011. View

12.

Srichai M, Lim R, Wong S, Lee V . Cardiovascular applications of phase-contrast MRI. AJR Am J Roentgenol. 2009; 192(3):662-75. DOI: 10.2214/AJR.07.3744. View

13.

Vasan R, Benjamin E, Levy D . Prevalence, clinical features and prognosis of diastolic heart failure: an epidemiologic perspective. J Am Coll Cardiol. 1995; 26(7):1565-74. DOI: 10.1016/0735-1097(95)00381-9. View

14.

Lotz J, Meier C, Leppert A, Galanski M . Cardiovascular flow measurement with phase-contrast MR imaging: basic facts and implementation. Radiographics. 2002; 22(3):651-71. DOI: 10.1148/radiographics.22.3.g02ma11651. View

15.

Hoskins P . Accuracy of maximum velocity estimates made using Doppler ultrasound systems. Br J Radiol. 1996; 69(818):172-7. DOI: 10.1259/0007-1285-69-818-172. View

16.

van den Hout R, Lamb H, van den Aardweg J, Schot R, Steendijk P, van der Wall E . Real-time MR imaging of aortic flow: influence of breathing on left ventricular stroke volume in chronic obstructive pulmonary disease. Radiology. 2003; 229(2):513-9. DOI: 10.1148/radiol.2292020559. View

17.

Rathi V, Doyle M, Yamrozik J, Williams R, Caruppannan K, Truman C . Routine evaluation of left ventricular diastolic function by cardiovascular magnetic resonance: a practical approach. J Cardiovasc Magn Reson. 2008; 10:36. PMC: 2481245. DOI: 10.1186/1532-429X-10-36. View

18.

Hamilton C, Moran P, Santago 2nd P, Rajala S . Effects of intravoxel velocity distributions on the accuracy of the phase-mapping method in phase-contrast MR angiography. J Magn Reson Imaging. 1994; 4(5):752-5. DOI: 10.1002/jmri.1880040520. View

19.

Kovacs S, Meisner J, Yellin E . Modeling of diastole. Cardiol Clin. 2000; 18(3):459-87. DOI: 10.1016/s0733-8651(05)70156-9. View

20.

Zile M, Brutsaert D . New concepts in diastolic dysfunction and diastolic heart failure: Part I: diagnosis, prognosis, and measurements of diastolic function. Circulation. 2002; 105(11):1387-93. DOI: 10.1161/hc1102.105289. View