Interkingdom Gene Transfer May Contribute to the Evolution of Phytopathogenicity in Botrytis Cinerea

Overview

Journal Evol Bioinform Online

Publisher Sage Publications

Specialty Biology

Date 2012 Feb 21

PMID 22346340

Citations 2

Authors

Bo Zhu

Qing Zhou

Guanlin Xie

GuoQing Zhang

Xiaowei Zhang

Yanli Wang

Gunchang Sun

Bin Li

Gulei Jin

Affiliations

Soon will be listed here.

Abstract

The ascomycete Botrytis cinerea is a phytopathogenic fungus infecting and causing significant yield losses in a number of crops. The genome of B. cinerea has been fully sequenced while the importance of horizontal gene transfer (HGT) to extend the host range in plant pathogenic fungi has been recently appreciated. However, recent data confirm that the B. cinerea fungus shares conserved virulence factors with other fungal plant pathogens with narrow host range. Therefore, interkingdom HGT may contribute to the evolution of phytopathogenicity in B. cinerea. In this study, a stringent genome comparison pipeline was used to identify potential genes that have been obtained by B. cinerea but not by other fungi through interkingdom HGT. This search led to the identification of four genes: a UDP-glucosyltransferase (UGT), a lipoprotein and two alpha/beta hydrolase fold proteins. Phylogenetic analysis of the four genes suggests that B. cinerea acquired UGT from plants and the other 3 genes from bacteria. Based on the known gene functions and literature searching, a correlation between gene acquision and the evolution of pathogenicity in B. cinerea can be postulated.

Citing Articles

From Natural Hosts to Agricultural Threats: The Evolutionary Journey of Phytopathogenic Fungi.

Madhushan A, Weerasingha D, Ilyukhin E, Taylor P, Ratnayake A, Liu J J Fungi (Basel). 2025; 11(1).

PMID: 39852444 PMC: 11766330. DOI: 10.3390/jof11010025.

Contribution of Multiple Inter-Kingdom Horizontal Gene Transfers to Evolution and Adaptation of Amphibian-Killing Chytrid, Batrachochytrium dendrobatidis.

Sun B, Li T, Xiao J, Liu L, Zhang P, Murphy R Front Microbiol. 2016; 7:1360.

PMID: 27630622 PMC: 5005798. DOI: 10.3389/fmicb.2016.01360.

Nothing in Evolution Makes Sense Except in the Light of Genomics: Read-Write Genome Evolution as an Active Biological Process.

Shapiro J Biology (Basel). 2016; 5(2).

PMID: 27338490 PMC: 4929541. DOI: 10.3390/biology5020027.

References

Mallet L, Becq J, Deschavanne P . Whole genome evaluation of horizontal transfers in the pathogenic fungus Aspergillus fumigatus. BMC Genomics. 2010; 11:171. PMC: 2848249. DOI: 10.1186/1471-2164-11-171. View

Cohen O, Pupko T . Inference and characterization of horizontally transferred gene families using stochastic mapping. Mol Biol Evol. 2009; 27(3):703-13. PMC: 2822287. DOI: 10.1093/molbev/msp240. View

Stefanato F, Abou-Mansour E, Buchala A, Kretschmer M, Mosbach A, Hahn M . The ABC transporter BcatrB from Botrytis cinerea exports camalexin and is a virulence factor on Arabidopsis thaliana. Plant J. 2009; 58(3):499-510. DOI: 10.1111/j.1365-313X.2009.03794.x. View

Sepulveda-Jimenez G, Rueda-Benitez P, Porta H, Rocha-Sosa M . A red beet (Beta vulgaris) UDP-glucosyltransferase gene induced by wounding, bacterial infiltration and oxidative stress. J Exp Bot. 2004; 56(412):605-11. DOI: 10.1093/jxb/eri036. View

Dagan T, Artzy-Randrup Y, Martin W . Modular networks and cumulative impact of lateral transfer in prokaryote genome evolution. Proc Natl Acad Sci U S A. 2008; 105(29):10039-44. PMC: 2474566. DOI: 10.1073/pnas.0800679105. View

Slot J, Rokas A . Horizontal transfer of a large and highly toxic secondary metabolic gene cluster between fungi. Curr Biol. 2011; 21(2):134-9. DOI: 10.1016/j.cub.2010.12.020. View

Schmidt H, Strimmer K, Vingron M, von Haeseler A . TREE-PUZZLE: maximum likelihood phylogenetic analysis using quartets and parallel computing. Bioinformatics. 2002; 18(3):502-4. DOI: 10.1093/bioinformatics/18.3.502. View

Stiller J . Experimental design and statistical rigor in phylogenomics of horizontal and endosymbiotic gene transfer. BMC Evol Biol. 2011; 11:259. PMC: 3190393. DOI: 10.1186/1471-2148-11-259. View

Gojkovic Z, Knecht W, Zameitat E, Warneboldt J, Coutelis J, Pynyaha Y . Horizontal gene transfer promoted evolution of the ability to propagate under anaerobic conditions in yeasts. Mol Genet Genomics. 2004; 271(4):387-93. DOI: 10.1007/s00438-004-0995-7. View

10.

Ohsugi M, Imanishi Y . Microbiological activity of biotin-vitamers. J Nutr Sci Vitaminol (Tokyo). 1985; 31(6):563-72. DOI: 10.3177/jnsv.31.563. View

11.

Choquer M, Fournier E, Kunz C, Levis C, Pradier J, Simon A . Botrytis cinerea virulence factors: new insights into a necrotrophic and polyphageous pathogen. FEMS Microbiol Lett. 2007; 277(1):1-10. DOI: 10.1111/j.1574-6968.2007.00930.x. View

12.

Thompson J, Higgins D, Gibson T . CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 1994; 22(22):4673-80. PMC: 308517. DOI: 10.1093/nar/22.22.4673. View

13.

Poppenberger B, Berthiller F, Lucyshyn D, Sieberer T, Schuhmacher R, Krska R . Detoxification of the Fusarium mycotoxin deoxynivalenol by a UDP-glucosyltransferase from Arabidopsis thaliana. J Biol Chem. 2003; 278(48):47905-14. DOI: 10.1074/jbc.M307552200. View

14.

Shimodaira H, Hasegawa M . CONSEL: for assessing the confidence of phylogenetic tree selection. Bioinformatics. 2001; 17(12):1246-7. DOI: 10.1093/bioinformatics/17.12.1246. View

15.

Castresana J . Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis. Mol Biol Evol. 2000; 17(4):540-52. DOI: 10.1093/oxfordjournals.molbev.a026334. View

16.

Mehrabi R, Bahkali A, Abd-Elsalam K, Moslem M, Ben MBarek S, Mirzadi Gohari A . Horizontal gene and chromosome transfer in plant pathogenic fungi affecting host range. FEMS Microbiol Rev. 2011; 35(3):542-54. DOI: 10.1111/j.1574-6976.2010.00263.x. View

17.

Ten Have A, Espino J, Dekkers E, Van Sluyter S, Brito N, Kay J . The Botrytis cinerea aspartic proteinase family. Fungal Genet Biol. 2009; 47(1):53-65. DOI: 10.1016/j.fgb.2009.10.008. View

18.

Andersson J . Lateral gene transfer in eukaryotes. Cell Mol Life Sci. 2005; 62(11):1182-97. PMC: 11138376. DOI: 10.1007/s00018-005-4539-z. View

19.

Mei G, Yan X, Turak A, Luo Z, Zhang L . AidH, an alpha/beta-hydrolase fold family member from an Ochrobactrum sp. strain, is a novel N-acylhomoserine lactonase. Appl Environ Microbiol. 2010; 76(15):4933-42. PMC: 2916461. DOI: 10.1128/AEM.00477-10. View

20.

Keane T, Creevey C, Pentony M, Naughton T, Mclnerney J . Assessment of methods for amino acid matrix selection and their use on empirical data shows that ad hoc assumptions for choice of matrix are not justified. BMC Evol Biol. 2006; 6:29. PMC: 1435933. DOI: 10.1186/1471-2148-6-29. View