» Articles » PMID: 22344520

Commercialization of Microfluidic Point-of-care Diagnostic Devices

Overview
Journal Lab Chip
Specialties Biotechnology
Chemistry
Date 2012 Feb 21
PMID 22344520
Citations 241
Authors
Affiliations
Soon will be listed here.
Abstract

A large part of the excitement behind microfluidics is in its potential for producing practical devices, but surprisingly few lab-on-a-chip based technologies have been successfully introduced into the market. Here, we review current work in commercializing microfluidic technologies, with a focus on point-of-care diagnostics applications. We will also identify challenges to commercialization, including lessons drawn from our experience in Claros Diagnostics. Moving forward, we discuss the need to strike a balance between achieving real-world impact with integrated devices versus design of novel single microfluidic components.

Citing Articles

Deep Learning-Enhanced Portable Chemiluminescence Biosensor: 3D-Printed, Smartphone-Integrated Platform for Glucose Detection.

Singhal C, Kaushik V, Awasthi A, Zalke J, Palekar S, Rewatkar P Bioengineering (Basel). 2025; 12(2).

PMID: 40001639 PMC: 11851613. DOI: 10.3390/bioengineering12020119.


Real-World Implementation of Particle-Based Microfluidics: On-Spot Test for Iron and Copper Ions in Water.

Saar I, Evard H ACS Omega. 2025; 10(1):1800-1808.

PMID: 39829583 PMC: 11740257. DOI: 10.1021/acsomega.4c10152.


A Novel Size-Based Centrifugal Microfluidic Design to Enrich and Magnetically Isolate Circulating Tumor Cells from Blood Cells through Biocompatible Magnetite-Arginine Nanoparticles.

Farahinia A, Khani M, Morhart T, Wells G, Badea I, Wilson L Sensors (Basel). 2024; 24(18).

PMID: 39338775 PMC: 11436177. DOI: 10.3390/s24186031.


Vibration mixing for enhanced paper-based recombinase polymerase amplification.

Shimazu K, Bender A, Reinhall P, Posner J Lab Chip. 2024; 24(20):4879-4891.

PMID: 39302137 PMC: 11534347. DOI: 10.1039/d4lc00592a.


Advancing Microfluidic Immunity Testing Systems: New Trends for Microbial Pathogen Detection.

Wang Y, Chen J, Zhang Y, Yang Z, Zhang K, Zhang D Molecules. 2024; 29(14).

PMID: 39064900 PMC: 11279515. DOI: 10.3390/molecules29143322.