(D, L) Polylactide Microspheres As Embolic Agent. A Preliminary Study

Overview

Journal Neuroradiology

Specialties Neurology
Radiology

Date 1990 Jan 1

PMID 2234391

Citations 7

Authors

P Flandroy

C Grandfils

J Collignon

A Thibaut

N Nihant

S Barbette

R Jerome

P TEYSSIE

Affiliations

Soon will be listed here.

Abstract

Owing to their shape, accurately calibrated microspheres appear to be very suitable material for distal embolization. Moreover, the biocompatible (D, L) polyactide (PLA) microspheres possess two other valuable advantages: easy adjustment of their biodegradation rate, and incorporation of chemotherapeutic agents during their production. The authors describe the preparation of these (D, L) PLA microspheres and their clinical applications as a preliminary step to arterial chemoembolization.

Citing Articles

Differences and Advantages of Particles versus Liquid Material for Preoperative Intracranial Tumor Embolization: A Retrospective Multicenter Study.

Iida Y, Akimoto T, Miyake S, Suzuki R, Shimohigoshi W, Hori S J Neuroendovasc Ther. 2024; 18(4):110-118.

PMID: 38721619 PMC: 11076144. DOI: 10.5797/jnet.oa.2023-0083.

Microparticles prepared from sulfenamide-based polymers.

DMello S, Yoo J, Bowden N, Salem A J Microencapsul. 2013; 31(2):137-46.

PMID: 23862723 PMC: 4295722. DOI: 10.3109/02652048.2013.814728.

Preoperative cellulose porous beads for therapeutic embolization of meningioma: provocation test and technical considerations.

Kai Y, Hamada J, Morioka M, Yano S, Nakamura H, Makino K Neuroradiology. 2007; 49(5):437-43.

PMID: 17318600 DOI: 10.1007/s00234-007-0218-0.

Clinical evaluation of cellulose porous beads for the therapeutic embolization of meningiomas.

Kai Y, Hamada J, Morioka M, Yano S, Nakamura H, Makino K AJNR Am J Neuroradiol. 2006; 27(5):1146-50.

PMID: 16687561 PMC: 7975727.

The utility of the microcrystalline cellulose sphere as a particulate embolic agent: an experimental study.

Kai Y, Hamada J, Morioka M, Todaka T, Hasegawa S, Ushio Y AJNR Am J Neuroradiol. 2000; 21(6):1160-3.

PMID: 10871033 PMC: 7973907.

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