Cellular Transport and Homeostasis of Essential and Nonessential Metals

Overview

Journal Metallomics

Publisher Oxford University Press

Date 2012 Feb 17

PMID 22337135

Citations 50

Authors

Ebany J Martinez-Finley

Sudipta Chakraborty

Stephanie J B Fretham

Michael Aschner

Affiliations

Soon will be listed here.

Abstract

Metals can have a number of detrimental or beneficial effects in the cell, but first they must get in. Organisms have evolved transport mechanisms to get metals that are required, or essential into the cell. Nonessential metals often enter the cell through use of the machinery provided for essential metals. Much work has been done to advance our understanding of how these metals are transported across plasma and organelle membranes. This review provides an overview of essential and nonessential metal transport and homeostatic processes.

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