Desquamative Interstitial Pneumonitis in a Patient with Systemic Lupus Erythematosus
Overview
Affiliations
Desquamative interstitial pneumonia (DIP) is a rare form of interstitial lung disease (ILD) commonly found among healthy smokers. ILD is a rare manifestation of systemic lupus erythematosus (SLE), and typically associated with a histopathological pattern of nonspecific interstitial pneumonia (NSIP). The present article describes an unusual case of DIP in a nonsmoking patient with SLE presenting as NSIP. DIP can occur in the context of SLE in patients with a negative smoking history, and clinicians should consider lung biopsy to correctly classify ILD with unusual presentation on computed tomography scan.
Brady D, Berkowitz E, Sharma A, Ackman J, Bernheim A, Chung M Radiol Cardiothorac Imaging. 2021; 3(4):e200625.
PMID: 34498003 PMC: 8415141. DOI: 10.1148/ryct.2021200625.
Chen Y, Wang Y, Chen X, Liang H, Yang X Arch Rheumatol. 2020; 35(2):239-246.
PMID: 32851373 PMC: 7406170. DOI: 10.46497/ArchRheumatol.2020.7583.
Desquamative interstitial pneumonia: a systematic review of its features and outcomes.
Hellemons M, Moor C, Von Der Thusen J, Rossius M, Odink A, Thorgersen L Eur Respir Rev. 2020; 29(156).
PMID: 32581140 PMC: 9488565. DOI: 10.1183/16000617.0181-2019.
Overlaps and uncertainties of smoking-related idiopathic interstitial pneumonias.
Bak S, Lee H Int J Chron Obstruct Pulmon Dis. 2017; 12:3221-3229.
PMID: 29138550 PMC: 5677302. DOI: 10.2147/COPD.S146899.
Chance, genetics, and the heterogeneity of disease and pathogenesis in systemic lupus erythematosus.
Marion T, Postlethwaite A Semin Immunopathol. 2014; 36(5):495-517.
PMID: 25102991 DOI: 10.1007/s00281-014-0440-x.