Using Salivary Cotinine to Validate Self-reports of Tobacco Use by Indian Youth Living in Low-income Neighborhoods
Overview
Authors
Affiliations
Background: Self-reported tobacco use among young people can underestimate the actual prevalence of tobacco use. Biochemical validation of self-reports is particularly recommended for intervention studies where cessation outcomes are to be measured. Literature on biochemical validation of self-reports of multiple forms of tobacco use in India is sparse, particularly among young people.
Methods: The study was conducted during the baseline household survey of a community-based tobacco prevention and cessation intervention trial for youth (10-19 years old) residing in slum communities in Delhi, India in 2009. Salivary cotinine measurement on 1,224 samples showed that youth were under-reporting use of chewing and smoking tobacco.
Results: Self-reports had a low sensitivity (36.3%) and a positive predictive value of 72.6%. No statistically significant difference in under- reporting was found between youth in the control and intervention conditions of the trial, which will be taken into consideration in assessing intervention outcomes at a later time point.
Conclusion: Biochemical validation of self-reported tobacco use should be considered during prevention and cessation studies among youth living in low-income settings in developing countries like India.
Impact: The future results of biochemical validation from Project ACTIVITY (Advancing Cessation of Tobacco in Vulnerable Indian Tobacco Consuming Youth) will be useful to design validation studies in resource-poor settings.
Halima Allahdad A, Ngari M, Kibiti C, Udu Yusuf R, Mutua S, Budambula V Glob Health Epidemiol Genom. 2024; 2024:5653709.
PMID: 39206219 PMC: 11357821. DOI: 10.1155/2024/5653709.
Zech J, Patel T, Zvolensky M, Schmidt N, Cougle J Behav Res Ther. 2024; 175:104499.
PMID: 38412574 PMC: 11008596. DOI: 10.1016/j.brat.2024.104499.
Factors Influencing Tobacco Cessation in India: Findings from the Global Adult Tobacco Survey-2.
Mini G, Jayakrishnan R, Jishnu K, Anil K Asian Pac J Cancer Prev. 2023; 24(11):3749-3756.
PMID: 38019232 PMC: 10772769. DOI: 10.31557/APJCP.2023.24.11.3749.
Purushothama C, Crape B, Stolyarov V, Jaxybayeva A, la Fleur P, Olickal J PLoS One. 2023; 18(11):e0292490.
PMID: 38011129 PMC: 10681200. DOI: 10.1371/journal.pone.0292490.
Influence of cigarette smoking on allergic rhinitis: a comparative study on smokers and non-smokers.
Grillo C, La Mantia I, Grillo C, Ciprandi G, Ragusa M, Andaloro C Acta Biomed. 2019; 90(7-S):45-51.
PMID: 31292427 PMC: 6776172. DOI: 10.23750/abm.v90i7-S.8658.