Protein-protected Luminescent Noble Metal Quantum Clusters: an Emerging Trend in Atomic Cluster Nanoscience

Overview

Journal Nano Rev

Specialty Biotechnology

Date 2012 Feb 8

PMID 22312454

Citations 16

Authors

Paulrajpillai Lourdu Xavier

Kamalesh Chaudhari

Ananya Baksi

Thalappil Pradeep

Affiliations

Soon will be listed here.

Abstract

Noble metal quantum clusters (NMQCs) are the missing link between isolated noble metal atoms and nanoparticles. NMQCs are sub-nanometer core sized clusters composed of a group of atoms, most often luminescent in the visible region, and possess intriguing photo-physical and chemical properties. A trend is observed in the use of ligands, ranging from phosphines to functional proteins, for the synthesis of NMQCs in the liquid phase. In this review, we briefly overview recent advancements in the synthesis of protein protected NMQCs with special emphasis on their structural and photo-physical properties. In view of the protein protection, coupled with direct synthesis and easy functionalization, this hybrid QC-protein system is expected to have numerous optical and bioimaging applications in the future, pointers in this direction are visible in the literature.

Citing Articles

Recent Progress on Ligand-Protected Metal Nanoclusters in Photocatalysis.

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Rapid Detection of Ag(I) via Size-Induced Photoluminescence Quenching of Biocompatible Green-Emitting, l-Tryptophan-Scaffolded Copper Nanoclusters.

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Structure and luminescence of DNA-templated silver clusters.

Gonzalez-Rosell A, Cerretani C, Mastracco P, Vosch T, Copp S Nanoscale Adv. 2022; 3(5):1230-1260.

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Relative Populations and IR Spectra of Cu Cluster at Finite Temperature Based on DFT and Statistical Thermodynamics Calculations.

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References

Hu D, Sheng Z, Gong P, Zhang P, Cai L . Highly selective fluorescent sensors for Hg(2+) based on bovine serum albumin-capped gold nanoclusters. Analyst. 2010; 135(6):1411-6. DOI: 10.1039/c000589d. View

Lee W, Bae Y, Bard A . Strong blue photoluminescence and ECL from OH-terminated PAMAM dendrimers in the absence of gold nanoparticles. J Am Chem Soc. 2004; 126(27):8358-9. DOI: 10.1021/ja0475914. View

Wei W, Lu Y, Chen W, Chen S . One-pot synthesis, photoluminescence, and electrocatalytic properties of subnanometer-sized copper clusters. J Am Chem Soc. 2011; 133(7):2060-3. DOI: 10.1021/ja109303z. View

Guo C, Irudayaraj J . Fluorescent Ag clusters via a protein-directed approach as a Hg(II) ion sensor. Anal Chem. 2011; 83(8):2883-9. DOI: 10.1021/ac1032403. View

Jones R . What can biology teach us?. Nat Nanotechnol. 2008; 1(2):85-6. DOI: 10.1038/nnano.2006.116. View

Goswami N, Makhal A, Kumar Pal S . Toward an alternative intrinsic probe for spectroscopic characterization of a protein. J Phys Chem B. 2010; 114(46):15236-43. DOI: 10.1021/jp105943d. View

Wei H, Wang Z, Zhang J, House S, Gao Y, Yang L . Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme. Nat Nanotechnol. 2011; 6(2):93-7. DOI: 10.1038/nnano.2010.280. View

Udayabhaskararao T, Sun Y, Goswami N, Pal S, Balasubramanian K, Pradeep T . Ag7Au6: a 13-atom alloy quantum cluster. Angew Chem Int Ed Engl. 2012; 51(9):2155-9. DOI: 10.1002/anie.201107696. View

Maity P, Tsunoyama H, Yamauchi M, Xie S, Tsukuda T . Organogold clusters protected by phenylacetylene. J Am Chem Soc. 2011; 133(50):20123-5. DOI: 10.1021/ja209236n. View

10.

Kawasaki H, Yoshimura K, Hamaguchi K, Arakawa R . Trypsin-stabilized fluorescent gold nanocluster for sensitive and selective Hg2+ detection. Anal Sci. 2011; 27(6):591-6. DOI: 10.2116/analsci.27.591. View

11.

Rao T, Nataraju B, Pradeep T . Ag(9) quantum cluster through a solid-state route. J Am Chem Soc. 2010; 132(46):16304-7. DOI: 10.1021/ja105495n. View

12.

Sun C, Yang H, Yuan Y, Tian X, Wang L, Guo Y . Controlling assembly of paired gold clusters within apoferritin nanoreactor for in vivo kidney targeting and biomedical imaging. J Am Chem Soc. 2011; 133(22):8617-24. DOI: 10.1021/ja200746p. View

13.

Dhanalakshmi L, Udayabhaskararao T, Pradeep T . Conversion of double layer charge-stabilized Ag@citrate colloids to thiol passivated luminescent quantum clusters. Chem Commun (Camb). 2011; 48(6):859-61. DOI: 10.1039/c1cc15604g. View

14.

Shankar S, Rai A, Ankamwar B, Singh A, Ahmad A, Sastry M . Biological synthesis of triangular gold nanoprisms. Nat Mater. 2004; 3(7):482-8. DOI: 10.1038/nmat1152. View

15.

Templeton A, Wuelfing W, Murray R . Monolayer-protected cluster molecules. Acc Chem Res. 2000; 33(1):27-36. DOI: 10.1021/ar9602664. View

16.

Goswami N, Giri A, Bootharaju M, Xavier P, Pradeep T, Kumar Pal S . Copper quantum clusters in protein matrix: potential sensor of Pb2+ ion. Anal Chem. 2011; 83(24):9676-80. DOI: 10.1021/ac202610e. View

17.

Yu J, Choi S, Dickson R . Shuttle-based fluorogenic silver-cluster biolabels. Angew Chem Int Ed Engl. 2008; 48(2):318-20. PMC: 2790050. DOI: 10.1002/anie.200804137. View

18.

Panzner M, Bilinovich S, Youngs W, Leeper T . Silver metallation of hen egg white lysozyme: X-ray crystal structure and NMR studies. Chem Commun (Camb). 2011; 47(46):12479-81. PMC: 3677188. DOI: 10.1039/c1cc15908a. View

19.

Wu Z, Jin R . On the ligand's role in the fluorescence of gold nanoclusters. Nano Lett. 2010; 10(7):2568-73. DOI: 10.1021/nl101225f. View

20.

Wang Y, Cui Y, Zhao Y, Liu R, Sun Z, Li W . Bifunctional peptides that precisely biomineralize Au clusters and specifically stain cell nuclei. Chem Commun (Camb). 2011; 48(6):871-3. DOI: 10.1039/c1cc15926g. View