Nutritional Outcomes Following Gastrostomy in Children with Cystic Fibrosis

Overview

Journal Pediatr Pulmonol

Specialties Pediatrics
Pulmonary Medicine

Date 2012 Feb 3

PMID 22298389

Citations 7

Authors

Gia M Bradley

Kathryn A Carson

Amanda R Leonard

Peter J Mogayzel Jr

Maria Oliva-Hemker

Affiliations

Soon will be listed here.

Abstract

Objective: In 2005 the Cystic Fibrosis (CF) Foundation recommended that children with CF maintain a body mass index (BMI) ≥ 50th percentile. Our study evaluated if gastrostomy (GT) placement increases the likelihood of reaching that goal compared to a standardized nutrition protocol.

Study Design: Retrospective study of 20 children with CF ages 2-20 years with GTs placed from 2005 to 2010. Each case was pair-matched on age, sex, pancreatic status, BMI, and lung function with a nonGT child with CF. Outcome measures included nutritional status and lung function at 6 months and 1 year.

Results: At baseline, mean ± SD BMI Z-scores were similar (cases -1.19 ± 0.60, controls -1.10 ± 0.50; P = 0.10). Cases had a significant 6-month increase in mean BMI Z-score to -0.29 ± 0.84 compared to -1.02 ± 0.67 for controls (P < 0.001). By 1 year, the change in mean BMI Z-score was less different (cases -0.41 ± 0.76, controls -0.71 ± 0.51; P = 0.07). Both groups had stable lung function. From exact logistic regression analysis, the odds ratio for cases compared to controls of reaching BMI ≥ 50th percentile was 9.70 (95% CI: 1.05-484.7; P = 0.04) at 6 months and 3.65 (95%CI: 0.69-25.86; P = 0.16) at 1 year.

Conclusion: Our study suggests that children with CF who receive GTs are more likely to achieve BMI ≥ 50th percentile than matched children without GTs.

Citing Articles

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Early life growth trajectories in cystic fibrosis are associated with lung function at age six.

Psoter K, Dickinson K, Riekert K, Collaco J J Cyst Fibros. 2023; 22(3):395-401.

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Enteral tube feeding for cystic fibrosis.

Shimmin D, Lowdon J, Remmington T Cochrane Database Syst Rev. 2019; 7:CD001198.

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Nutritional Outcome in Home Gastrostomy-Fed Children with Chronic Diseases.

Martinez-Costa C, Calderon C, Gomez-Lopez L, Borraz S, Crehua-Gaudiza E, Pedron-Giner C Nutrients. 2019; 11(5).

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