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Lymphangioma: Is Intralesional Bleomycin Sclerotherapy Effective?

Overview
Journal Biomed Imaging Interv J
Specialty Radiology
Date 2012 Jan 27
PMID 22279495
Citations 17
Authors
Z Rozman
R R Thambidorai
A M Zaleha
Z Zakaria
M A Zulfiqar
Affiliations
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Abstract

Purpose: This study aims to evaluate the effectiveness of intralesional bleomycin sclerotherapy in the treatment of lymphangioma in children and to determine the incidence of complications in the treatment.

Methods: This is a retrospective study of 24 children diagnosed with lymphangioma and treated with intralesional injection of bleomycin aqueous solution from January 1999 to December 2004.

Results: Complete resolution was seen in 63% (15/24) of lesions, 21% (5/24) had good response and 16% (4/24) had poor response. The tumour recurred in 2 patients. Two other patients had abscess formation at the site of injection. No other serious complications or side effects were observed.

Conclusion: Intralesional bleomycin therapy was very effective in the treatment of lymphangioma. Our results were comparable to other published studies. Bleomycin administered as intralesional injection was found to be safe as there was no serious complication or side effect observed in this study.

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