» Articles » PMID: 22279254

Association of Overweight and Obesity with Breast Cancer in India

Overview
Date 2012 Jan 27
PMID 22279254
Citations 11
Authors
Affiliations
Soon will be listed here.
Abstract

Background: In women, cancer of the breast is one of the most common incident cancer and cause of death from cancer. Anthropometric factors of weight, height, and body mass index (BMI) have been associated with breast cancer risk.

Objectives: To study the association of overweight and obesity with breast cancer in India.

Materials And Methods: A hospital-based matched case-control study was conducted. Three hundred and twenty newly diagnosed breast cancer patients and three hundred and twenty normal healthy individuals constituted the study population. The subjects in the control group were matched individually with the patients for their age ±2 years and socioeconomic status. Anthropometric measurements of weight and height were recorded utilizing the standard equipments and methodology. The paired 't' test and univariate logistic regression analysis were carried out.

Results: It was observed that the patients had a statistically higher mean weight, body mass index, and mid upper arm circumference as compared to the controls. It was observed that the risk of breast cancer increased with increasing levels of BMI. Overweight and obese women had Odd's redio of 1.06 and 2.27, respectively, as compared to women with normal weight.

Conclusions: The results of the present study revealed a strong association of overweight and obesity with breast cancer in the Indian population.

Citing Articles

Estimation of fatty acid composition in mammary adipose tissue using deep neural network with unsupervised training.

Chaudhary S, Lane E, Levy A, McGrath A, Mema E, Reichmann M Magn Reson Med. 2024; 93(5):2163-2175.

PMID: 39641987 PMC: 11893257. DOI: 10.1002/mrm.30401.


Modifiable (Sleeping Pattern and Stress) and Non-Modifiable Risk Factors Associated with Breast Cancer: A Matched Case-Control Study in Delhi, India.

Vishwakarma G, Mehta A, Saifi M, Garg D, Paliwal D Asian Pac J Cancer Prev. 2022; 23(7):2469-2476.

PMID: 35901355 PMC: 9727361. DOI: 10.31557/APJCP.2022.23.7.2469.


Association between diabetes, obesity, aging, and cancer: review of recent literature.

Qiang J, Lipscombe L, Lega I Transl Cancer Res. 2022; 9(9):5743-5759.

PMID: 35117936 PMC: 8797908. DOI: 10.21037/tcr.2020.03.14.


Cost Effectiveness of Trastuzumab for Management of Breast Cancer in India.

Gupta N, Verma R, Gupta S, Prinja S JCO Glob Oncol. 2020; 6:205-216.

PMID: 32045547 PMC: 7051799. DOI: 10.1200/JGO.19.00293.


The Effects of Adipocytes on the Regulation of Breast Cancer in the Tumor Microenvironment: An Update.

Chu D, Nguyen Thi Phuong T, Tien N, Tran D, Nguyen T, Thanh V Cells. 2019; 8(8).

PMID: 31398937 PMC: 6721665. DOI: 10.3390/cells8080857.


References
1.
Pathak D, Whittemore A . Combined effects of body size, parity, and menstrual events on breast cancer incidence in seven countries. Am J Epidemiol. 1992; 135(2):153-68. DOI: 10.1093/oxfordjournals.aje.a116268. View

2.
Zhu Z, Parviainen M, Mannisto S, Pietinen P, Eskelinen M, Syrjanen K . Vitamin E concentration in breast adipose tissue of breast cancer patients (Kuopio, Finland). Cancer Causes Control. 1996; 7(6):591-5. DOI: 10.1007/BF00051701. View

3.
Friedenreich C . Physical activity and cancer: lessons learned from nutritional epidemiology. Nutr Rev. 2001; 59(11):349-57. DOI: 10.1111/j.1753-4887.2001.tb06962.x. View

4.
. Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Committee. World Health Organ Tech Rep Ser. 1995; 854:1-452. View

5.
Li C, Malone K, White E, Daling J . Age when maximum height is reached as a risk factor for breast cancer among young U.S. women. Epidemiology. 1997; 8(5):559-65. DOI: 10.1097/00001648-199709000-00014. View