Putting the Pieces Together: Integrative Modeling Platform Software for Structure Determination of Macromolecular Assemblies

Overview

Journal PLoS Biol

Specialty Biology

Date 2012 Jan 25

PMID 22272186

Citations 280

Authors

Daniel Russel

Keren Lasker

Ben Webb

Javier Velazquez-Muriel

Elina Tjioe

Dina Schneidman-Duhovny

Bret Peterson

Andrej Sali

Affiliations

Soon will be listed here.

Abstract

A set of software tools for building and distributing models of macromolecular assemblies uses an integrative structure modeling approach, which casts the building of models as a computational optimization problem where information is encoded into a scoring function used to evaluate candidate models.

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