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Cancer Surgery in the Elderly

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Publisher Wiley
Specialty Biology
Date 2012 Jan 25
PMID 22272172
Citations 13
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Abstract

The proportions both of elderly patients in the world and of elderly patients with cancer are both increasing. In the evaluation of these patients, physiologic age, and not chronologic age, should be carefully considered in the decision-making process prior to both cancer screening and cancer treatment in an effort to avoid ageism. Many tools exist to help the practitioner determine the physiologic age of the patient, which allows for more appropriate and more individualized risk stratification, both in the pre- and postoperative periods as patients are evaluated for surgical treatments and monitored for surgical complications, respectively. During and after operations in the oncogeriatric populations, physiologic changes occuring that accompany aging include impaired stress response, increased senescence, and decreased immunity, all three of which impact the risk/benefit ratio associated with cancer surgery in the elderly.

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References
1.
Stamatiou K . Elderly and prostate cancer screening. Urol J. 2011; 8(2):83-7. View

2.
Koya D, Chen J, Smith T, Moran W . Screening mammography use in Medicare beneficiaries reflects 4-year mortality risk. Am J Med. 2011; 124(4):369.e1-8. DOI: 10.1016/j.amjmed.2010.11.019. View

3.
Quarini C, Gosney M . Review of the evidence for a colorectal cancer screening programme in elderly people. Age Ageing. 2009; 38(5):503-8. DOI: 10.1093/ageing/afp103. View

4.
Lewis C, Golin C, DeLeon C, Griffith J, Ivey J, Trevena L . A targeted decision aid for the elderly to decide whether to undergo colorectal cancer screening: development and results of an uncontrolled trial. BMC Med Inform Decis Mak. 2010; 10:54. PMC: 2949695. DOI: 10.1186/1472-6947-10-54. View

5.
Overcash J, Beckstead J, Moody L, Extermann M, Cobb S . The abbreviated comprehensive geriatric assessment (aCGA) for use in the older cancer patient as a prescreen: scoring and interpretation. Crit Rev Oncol Hematol. 2006; 59(3):205-10. DOI: 10.1016/j.critrevonc.2006.04.003. View