» Articles » PMID: 22262990

Effectiveness of Scraping and Mitomycin C to Treat Haze After Myopic Photorefractive Keratectomy

Overview
Publisher Bentham Open
Specialty Ophthalmology
Date 2012 Jan 21
PMID 22262990
Citations 3
Authors
Affiliations
Soon will be listed here.
Abstract

To report the possibility of post myopic photorefractive keratectomy (PRK) haze treatment in a patient with expressed reluctance for any additional laser therapy. Seven months after bilateral PRK with subsequent development of corneal haze and refractive regression in both eyes, a 37-old-year male patient presented a best-spectacle corrected visual acuity (BSCVA) of 20/30 in the right eye and of 20/22 in the left eye. Both eyes were sequentially treated by scraping the stromal surface and application of mitomycin C (MMC) for 2 minutes. Both eyes had significant improvement in corneal transparency. Eighteen months after this treatment BSCVA had improved to 20/20 in each eye. No toxic effects were observed during either re-epithelialization or follow-up periods. In conclusion scraping and application of MMC could be considered a good tool in the treatment of selected cases of haze after myopic PRK, especially with patients that are reluctant to undergo a secondary laser procedure.

Citing Articles

Topography-Guided Transepithelial Photorefractive Keratectomy for the Treatment of Persistent and Visually-Significant Adenoviral Corneal Infiltrates.

Spadea L, Di Genova L, Battagliola E, Paroli M Ther Clin Risk Manag. 2023; 19:341-349.

PMID: 37051278 PMC: 10084871. DOI: 10.2147/TCRM.S407503.


Main Complications of Photorefractive Keratectomy and their Management.

Spadea L, Giovannetti F Clin Ophthalmol. 2019; 13:2305-2315.

PMID: 31819355 PMC: 6885542. DOI: 10.2147/OPTH.S233125.


Corneal Regeneration After Photorefractive Keratectomy: A Review.

Tomas-Juan J, Murueta-Goyena Larranaga A, Hanneken L J Optom. 2014; 8(3):149-69.

PMID: 25444646 PMC: 4502084. DOI: 10.1016/j.optom.2014.09.001.

References
1.
Balestrazzi E, De Molfetta V, Spadea L, Vinciguerra P, Palmieri G, Santeusanio G . Histological, immunohistochemical, and ultrastructural findings in human corneas after photorefractive keratectomy. J Refract Surg. 1995; 11(3):181-7. View

2.
Vigo L, Scandola E, Carones F . Scraping and mitomycin C to treat haze and regression after photorefractive keratectomy for myopia. J Refract Surg. 2003; 19(4):449-54. DOI: 10.3928/1081-597X-20030701-12. View

3.
Qazi M, Johnson T, Pepose J . Development of late-onset subepithelial corneal haze after laser-assisted subepithelial keratectomy with prophylactic intraoperative mitomycin-C Case report and literature review. J Cataract Refract Surg. 2006; 32(9):1573-8. DOI: 10.1016/j.jcrs.2006.04.027. View

4.
Nassiri N, Farahangiz S, Rahnavardi M, Rahmani L, Nassiri N . Corneal endothelial cell injury induced by mitomycin-C in photorefractive keratectomy: nonrandomized controlled trial. J Cataract Refract Surg. 2008; 34(6):902-8. DOI: 10.1016/j.jcrs.2008.03.007. View

5.
Rajan M, OBrart D, Patmore A, Marshall J . Cellular effects of mitomycin-C on human corneas after photorefractive keratectomy. J Cataract Refract Surg. 2006; 32(10):1741-7. DOI: 10.1016/j.jcrs.2006.05.014. View