Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model

Overview

Journal Emerg Infect Dis

Specialty Infectious Diseases

Date 2012 Jan 21

PMID 22261009

Citations 21

Authors

Nadine Mestre-Frances

Simon Nicot

Sylvie Rouland

Anne-Gaelle Biacabe

Isabelle Quadrio

Armand Perret-Liaudet

Thierry Baron

Jean-Michel Verdier

Affiliations

Soon will be listed here.

Abstract

We report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue. After neurologic symptoms appeared, transmissibility of the disease by both inoculation routes was confirmed by detection of disease-associated prion protein in samples of brain tissue.

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