National Cancer Institute, National Heart, Lung and Blood Institute/Pediatric Blood and Marrow Transplantation Consortium First International Consensus Conference on Late Effects After Pediatric Hematopoietic Cell Transplantation: the Need For...

Overview

Journal Biol Blood Marrow Transplant

Date 2012 Jan 18

PMID 22248713

Citations 31

Authors

Michael A Pulsipher

Roderick Skinner

George B McDonald

Sangeeta Hingorani

Saro H Armenian

Kenneth R Cooke

Clarisa Gracia

Anna Petryk

Smita Bhatia

Nancy Bunin

Michael L Nieder

Christopher C Dvorak

Lillian Sung

Jean E Sanders

Joanne Kurtzberg

K Scott Baker

Affiliations

Soon will be listed here.

Abstract

Existing standards for screening and management of late effects occurring in children who have undergone hematopoietic cell transplantation (HCT) include recommendations from pediatric cancer networks and consensus guidelines from adult-oriented transplantation societies applicable to all HCT recipients. Although these approaches have significant merit, they are not pediatric HCT-focused, and they do not address post-HCT challenges faced by children with complex nonmalignant disorders. In this article we discuss the strengths and weaknesses of current published recommendations and conclude that pediatric-specific guidelines for post-HCT screening and management would be beneficial to the long-term health of these patients and would promote late effects research in this field. Our panel of late effects experts also provides recommendations for follow-up and therapy of selected post-HCT organ and endocrine complications in pediatric patients.

Citing Articles

Late Effects Following Hematopoietic Stem Cell Transplantation Among Childhood Transplant Survivors with Fanconi Anemia.

Ozkocer C, Visal Okur F, Demirbilek H, Altintas B, Cetin N, Kuskonmaz B Turk J Haematol. 2024; 42(1):15-24.

PMID: 39513346 PMC: 11869150. DOI: 10.4274/tjh.galenos.2024.2024.0189.

Review of acute kidney injury and progression to chronic kidney disease in pediatric patients undergoing hematopoietic cell transplant.

Vuong K, Joseph C, Angelo J Front Oncol. 2023; 13:1161709.

PMID: 37287918 PMC: 10242001. DOI: 10.3389/fonc.2023.1161709.

Endocrine sequelae of hematopoietic stem cell transplantation: Effects on mineral homeostasis and bone metabolism.

Miglietta F, Iamartino L, Palmini G, Giusti F, Marini F, Iantomasi T Front Endocrinol (Lausanne). 2023; 13:1085315.

PMID: 36714597 PMC: 9877332. DOI: 10.3389/fendo.2022.1085315.

Patient-reported long-term outcome following allogeneic hematopoietic stem cell transplantation in pediatric chronic myeloid leukemia.

Schleicher O, Horndasch A, Krumbholz M, Sembill S, Bremensdorfer C, Grabow D Front Oncol. 2022; 12:963223.

PMID: 36276159 PMC: 9580018. DOI: 10.3389/fonc.2022.963223.

Tandem hematopoietic stem cell transplant considerations in families with multiple siblings affected by DOCK8 deficiency.

Silbert S, Cole K, Bedoya S, Freeman A, Whangbo J, Avila D Bone Marrow Transplant. 2022; 57(11):1721-1723.

PMID: 35999252 PMC: 10391740. DOI: 10.1038/s41409-022-01778-4.

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