Intra-abdominal Cryptococcosis by Cryptococcus Gattii: Case Report and Review

Overview

Journal Mycopathologia

Specialties Microbiology
Pharmacology

Date 2012 Jan 17

PMID 22246960

Citations 6

Authors

Bruno S Araujo

Monica Bay

Roberta Reichert

Luciano Z Goldani

Affiliations

Soon will be listed here.

Abstract

Although abdominal cryptococcomas and visceral cryptococcal lymphadenitis as part of disseminated fungal infection have been reported mostly in HIV-infected patients, localized intra-abdominal involvement due to Cryptococcus gattii has not been previously described in non-HIV-infected patients. In general, a smaller proportion of cryptococcosis is caused by C. gattii. We report here on a type II diabetic HIV-negative patient who presented with a localized intra-abdominal cryptococcal mass due to C. gattii. In addition, we review the general aspects of intra-abdominal and gastrointestinal involvement by Cryptococcus neoformans in the literature and discuss the importance of identifying the C. neoformans varieties and C. gattii in routine laboratories.

Citing Articles

A Case of Cryptococcosis Due to a New Cryptococcus Neoformans Sequence Type in a Patient with Human Immunodeficiency Virus Infection.

Dai F, Yu Y, Lou J, Lu X Am J Trop Med Hyg. 2024; 112(2):373-376.

PMID: 39591644 PMC: 11803674. DOI: 10.4269/ajtmh.23-0818.

Multi-Locus Sequence Typing-Based Genetic Analysis, Antifungal Resistance, and Clinical Prognosis of Cryptococcus neoformans Infections in HIV-Infected Patients in Northern China.

Dai F, Yu Y, Lu X Am J Trop Med Hyg. 2024; 111(6):1184-1191.

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Distal jejunal obstruction due to and rifampicin-resistant co-infection: A case report.

Kasibante J, Kagimu E, Rutakingirwa M, Jjunju S, Tugume L, Meya D Med Mycol Case Rep. 2022; 38:44-47.

PMID: 36393997 PMC: 9649950. DOI: 10.1016/j.mmcr.2022.10.006.

Cryptococcosis complicating diabetes mellitus: a scoping review.

Nsenga L, Kajjimu J, Olum R, Ninsiima S, Kyazze A, Ssekamatte P Ther Adv Infect Dis. 2021; 8:20499361211014769.

PMID: 33996076 PMC: 8111545. DOI: 10.1177/20499361211014769.

Cryptococcosis caused by cryptococcus gattii: 2 case reports and literature review.

Xue X, Deng H, Zhao L, Zang X, Asuquo I, Meng M Medicine (Baltimore). 2020; 99(50):e23213.

PMID: 33327239 PMC: 7738107. DOI: 10.1097/MD.0000000000023213.

References

Speed B, Dunt D . Clinical and host differences between infections with the two varieties of Cryptococcus neoformans. Clin Infect Dis. 1995; 21(1):28-34; discussion 35-6. DOI: 10.1093/clinids/21.1.28. View

Daly J, Porter K, Chong F, Robillard R . Disseminated, nonmeningeal gastrointestinal cryptococcal infection in an HIV-negative patient. Am J Gastroenterol. 1990; 85(10):1421-4. View

Girardin M, Greloz V, Hadengue A . Cryptococcal gastroduodenitis: a rare location of the disease. Clin Gastroenterol Hepatol. 2009; 8(3):e28-9. DOI: 10.1016/j.cgh.2009.09.036. View

Saha S, Agarwal N, Srivastava A, Kumar A . Perforation peritonitis due to gastrointestinal cryptococcosis as an initial presentation in an AIDS patient. Singapore Med J. 2008; 49(11):e305-7. View

Scalfano Jr F, Prichard J, Lamki N, Athey P, GRAVES R . Abdominal cryptococcoma in AIDS: a case report. J Comput Tomogr. 1988; 12(3):237-9. DOI: 10.1016/0149-936x(88)90017-3. View

Pittarelli L . Photo quiz. Cryptococcoma. Clin Infect Dis. 1999; 29(4):759, 917. DOI: 10.1086/520428. View

Nawabi D, Ffolkes L, Obichere A . Cryptococcal small-bowel obstruction in an HIV-positive patient. J R Soc Med. 2005; 98(11):513-4. PMC: 1276000. DOI: 10.1177/014107680509801113. View

Sorrell T . Cryptococcus neoformans variety gattii. Med Mycol. 2001; 39(2):155-68. View

Markowitz S, Kerkering T, Gervin A . Biliary obstruction and cholestasis in AIDS: case report. Va Med. 1990; 117(3):114-6. View

10.

Sing Y, Ramdial P, Ibrahim T . Cryptococcosis masquerading as a tuboovarian abscess. Int J Gynecol Pathol. 2007; 27(1):37-40. DOI: 10.1097/pgp.0b013e318093fa11. View

11.

Pisarevsky A, Larriera A, Cean P, Petrucci E . [Pulmonary cryptococcoma with involvement of the chest wall in an immunocompetent patient]. Medicina (B Aires). 2010; 70(2):166-8. View

12.

Dora J, Kelbert S, Deutschendorf C, Cunha V, Aquino V, Pires Dos Santos R . Cutaneous cryptococccosis due to Cryptococcus gattii in immunocompetent hosts: case report and review. Mycopathologia. 2006; 161(4):235-8. DOI: 10.1007/s11046-006-0277-5. View

13.

Gordon S, Gal A, AMERSON J . Granulomatous peritoneal cryptococcomas. An unusual sequela of disseminated cryptococcosis. Arch Pathol Lab Med. 1994; 118(2):194-5. View

14.

Dong Z, Murphy J . Effects of the two varieties of Cryptococcus neoformans cells and culture filtrate antigens on neutrophil locomotion. Infect Immun. 1995; 63(7):2632-44. PMC: 173353. DOI: 10.1128/iai.63.7.2632-2644.1995. View

15.

Zou C, Yu Z, Tang L, Liang L, Zhao Z . Primary abdominal lymphonodular cryptococcosis in children: 2 case reports and a literature review. J Pediatr Surg. 2006; 41(3):e11-5. DOI: 10.1016/j.jpedsurg.2005.11.083. View

16.

Oliveira F, Severo C, Guazzelli L, Severo L . Cryptococcus gattii fungemia: report of a case with lung and brain lesions mimicking radiological features of malignancy. Rev Inst Med Trop Sao Paulo. 2007; 49(4):263-5. DOI: 10.1590/s0036-46652007000400014. View

17.

Chaitowitz M, Shaw M, Mokoena T . Gastrointestinal cryptococcosis presenting as spontaneous jejunal perforation in a nonimmunocompromised host. Dig Dis Sci. 2003; 48(6):1196-9. PMC: 7101658. DOI: 10.1023/a:1023797603364. View

18.

Chong P, PANABOKKE R, Chew K . Omental cryptococcoma. An unusual presentation of cryptococcosis. Arch Pathol Lab Med. 1986; 110(3):239-41. View

19.

Lehmann P, Morgan R, FREIMER E . Infection with Cryptococcus neoformans var. gattii leading to a pulmonary cryptococcoma and meningitis. J Infect. 1984; 9(3):301-6. DOI: 10.1016/s0163-4453(84)90772-2. View

20.

Springer D, Chaturvedi V . Projecting global occurrence of Cryptococcus gattii. Emerg Infect Dis. 2009; 16(1):14-20. PMC: 2874352. DOI: 10.3201/eid1601.090369. View