Empty Follicle Syndrome After GnRHa Triggering Versus HCG Triggering in COS

Overview

Journal J Assist Reprod Genet

Publisher Springer

Specialties Genetics
Reproductive Medicine

Date 2012 Jan 13

PMID 22237554

Citations 35

Authors

Juan C Castillo

Juan Garcia-Velasco

Peter Humaidan

Affiliations

Soon will be listed here.

Abstract

Purpose: This study aimed to explore the incidence of empty follicle syndrome (EFS) in oocyte donors who had final oocyte maturation triggered with GnRHa and to compare the incidence of EFS in this group of patients with IVF patients who had final oocyte maturation with hCG.

Methods: Data including 2034 oocyte donation cycles and 1433 IVF cycles performed between years 2009 and 2010 was retrospectively analyzed to identify cases of EFS in each group.

Results: The incidence of EFS in the two groups did not differ significantly, 3.5% versus 3.1%, (n.s.).

Conclusions: This large retrospective analysis indicates that the incidence of EFS is not increased after GnRHa triggering as compared to hCG triggering.

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GnRH agonist-only trigger, compared to dual trigger, reduces oocyte retrieval rate in high responders without affecting cumulative live birth rate.

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True empty follicle syndrome is a subtype of oocyte maturation abnormalities.

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Might retrigger with human chorionic gonadotropin be a solution for empty follicle syndrome after gonadotropin releasing hormone agonist trigger?.

Utkan Korun Z, Yuceturk A, Karaosmanoglu O, Cakiroglu Y, Tiras B Turk J Obstet Gynecol. 2024; 21(3):135-141.

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Mohammed-Durosinlorun A, Wada I Pan Afr Med J. 2024; 47:190.

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